N-(Deoxyguanosin-8-yl)-1-aminopyrene

Base Information

Chemical Name:N-(Deoxyguanosin-8-yl)-1-aminopyrene
CAS No.:85989-43-1
Molecular Formula:C₂₆H₂₂N₆O₄
Molecular Weight:482.498
Hs Code.:
Mol file:85989-43-1.mol

Synonyms:N-(deoxyguanosin-8-yl)-1-aminopyrene;2-Amino-9-((2R,4S,5R)-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-8-(pyren-1-ylamino)-1,9-dihydro-purin-6-one;

Suppliers and Price of N-(Deoxyguanosin-8-yl)-1-aminopyrene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2''-Deoxy-8-(1-pyrenylamino)guanosine
10mg
$ 1280.00

TRC
2''-Deoxy-8-(1-pyrenylamino)guanosine
2mg
$ 345.00

TRC
2''-Deoxy-8-(1-pyrenylamino)guanosine
1mg
$ 185.00

Total 5 raw suppliers

Chemical Property of N-(Deoxyguanosin-8-yl)-1-aminopyrene

Chemical Property:

Boiling Point:881.8°Cat760mmHg
Flash Point:487.1°C
PSA：151.31000
Density:1.74g/cm³
LogP:3.63770

Purity/Quality:

97% ^*data from raw suppliers

2''-Deoxy-8-(1-pyrenylamino)guanosine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 2''-Deoxy-8-(1-pyrenylamino)guanosine is used for gene mutations, oxidative DNA damage treatment and DNA adduct formation.

Technology Process of N-(Deoxyguanosin-8-yl)-1-aminopyrene

There total 12 articles about N-(Deoxyguanosin-8-yl)-1-aminopyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1174406-51-9
C₃₃H₂₈N₆O₄

: 85989-43-1
N-(deoxyguanosin-8-yl)-1-aminopyrene

Guidance literature:: With 1% Pd/C; In ethanol; cyclohexane;
DOI:10.1080/15257770902736426

Reference yield:

: 2-amino-9-[4-(tert-butyl-dimethyl-silanyloxy)-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-8-(pyren-1-ylamino)-1,9-dihydro-purin-6-one

: 85989-43-1
N-(deoxyguanosin-8-yl)-1-aminopyrene

Guidance literature:: With triethylamine tris(hydrogen fluoride); In tetrahydrofuran; at 20 ℃;
DOI:10.1016/S0040-4039(03)01484-9

Reference yield:

: 1714-29-0
1-bromopyrene

: 85989-43-1
N-(deoxyguanosin-8-yl)-1-aminopyrene

Guidance literature:: Multi-step reaction with 4 steps

1: 87 percent / KO-t-Bu; XANTPHOS / Pd₂dba3 / toluene / 2 h / 100 °C

2: ZnBr₂ / CH₂Cl₂; propan-2-ol

3: H₂ / Pd black / tetrahydrofuran / 0.5 h

4: Et₃N(HF)3 / tetrahydrofuran / 20 °C

With potassium tert-butylate; hydrogen; triethylamine tris(hydrogen fluoride); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; zinc dibromide; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; palladium; In tetrahydrofuran; dichloromethane; isopropyl alcohol; toluene;
DOI:10.1016/S0040-4039(03)01484-9