8-nitrooctan-1-ol

Base Information

• Chemical Name: 8-nitrooctan-1-ol
• CAS No.: 101972-90-1
• Molecular Formula: C₈H₁₇NO₃
• Molecular Weight: 175.228
• Mol file: 101972-90-1.mol

Synonyms:8-Nitro-1-octanol

Chemical Property of 8-nitrooctan-1-ol

Chemical Property:

• Vapor Pressure: 0.000413mmHg at 25°C
• Boiling Point: 281.8°Cat760mmHg
• Flash Point: 118.6°C
• Density: 1.025g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-nitrooctan-1-ol

There total 1 articles about 8-nitrooctan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

2-nitrocyclooctanone (13154-28-4) → 8-nitrooctan-1-ol (101972-90-1)

Guidance literature:

With sodium tetrahydroborate; In water; acetonitrile; for 2h; Ambient temperature;

DOI:10.1016/S0040-4020(01)89065-7

Reference yield:

8-nitrooctan-1-ol (101972-90-1) → 8-tetrahydropyranyloxyoctanal (57221-80-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Amberlyst 15 / CH₂Cl₂ / 2 h / Ambient temperature

2: 85 percent / 1.) KOH, 2.) KMnO₄, MgSO₄ / methanol / 0.5 h / 0 °C

With potassium hydroxide; potassium permanganate; Amberlyst 15; magnesium sulfate; In methanol; dichloromethane;

DOI:10.1080/00397919208019262

upstream raw materials:

2-nitrocyclooctanone

Downstream raw materials:

8-tetrahydropyranyloxyoctanal

Refernces

• 1、 Ballini, Roberto,Petrini, Marino,Rosini, Goffredo. "New and efficient synthesis of ω-nitroalcohols and spiroketals by chemio- and regioselective reductive cleavage of 2-nitrocycloalkanones". . p. 7531 - 7538. Retrieved 1990.