1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one

Base Information

Chemical Name:1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one
CAS No.:67565-05-3
Molecular Formula:C16H20N2O
Molecular Weight:256.348
Hs Code.:
DSSTox Substance ID:DTXSID70541354

Synonyms:67565-05-3;1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one;DTXSID70541354

Suppliers and Price of 1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one

Chemical Property:

XLogP3:2.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:256.157563266
Heavy Atom Count:19
Complexity:302

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)C(=O)CC(C1=CC=CC=C1)N2C=CN=C2

Technology Process of 1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one

There total 6 articles about 1-(1H-Imidazol-1-yl)-4,4-dimethyl-1-phenylpentan-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 288-32-4
1H-imidazole

: 538-44-3
4,4-dimethyl-1-phenyl-1-penten-3-one

: 67565-05-3
1-imidazol-1-yl-4,4-dimethyl-1-phenyl-pentan-3-one

Guidance literature:: With N-benzyl-trimethylammonium hydroxide; In pyridine; at 70 ℃; for 24h;

Reference yield: 6.0%

: 95546-35-3
1-bromo-4,4-dimethyl-1-phenyl-pentan-3-one

: 67565-05-3
1-imidazol-1-yl-4,4-dimethyl-1-phenyl-pentan-3-one

Guidance literature:: With potassium carbonate; In acetone; for 14h; Heating;

Reference yield:

: 75-97-8
3,3-dimethyl-butan-2-one

: 67565-05-3
1-imidazol-1-yl-4,4-dimethyl-1-phenyl-pentan-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: 1)Diisopropylamine, butyllithium / 1)ether, hexane,-30 deg C 2)-60 deg C, 5 min.

2: 90 percent / aq.HBr / diethyl ether / 12 h / 20 °C

3: 70 percent / Triton B / pyridine / 24 h / 70 °C

With n-butyllithium; hydrogen bromide; N-benzyl-trimethylammonium hydroxide; diisopropylamine; In pyridine; diethyl ether;