Moracin M

Base Information

• Chemical Name: Moracin M
• CAS No.: 56317-21-6
• Molecular Formula: C14H10O4
• Molecular Weight: 242.231
• UNII: L9FI83128D
• DSSTox Substance ID: DTXSID20204861
• Nikkaji Number: J380.396A
• Wikipedia: Moracin_M
• Wikidata: Q15634179
• Pharos Ligand ID: RDT4GZ24CNFW
• Metabolomics Workbench ID: 45977
• ChEMBL ID: CHEMBL512578
• Mol file: 56317-21-6.mol

Synonyms:moracin M

Chemical Property of Moracin M

Chemical Property:

• Vapor Pressure: 5.66E-06mmHg at 25°C
• Melting Point: 271-273℃
• Boiling Point: 369.3°Cat760mmHg
• Flash Point: 177.1°C
• PSA: 73.83000
• Density: 1.451g/cm³
• LogP: 3.21660
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 242.05790880
• Heavy Atom Count: 18
• Complexity: 286

Purity/Quality:

98%Min ^*data from raw suppliers

MoracinM ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=C1O)OC(=C2)C3=CC(=CC(=C3)O)O
• Uses: Moracin M is a tyrosinase inhibitory polyphenols from roots of Morus Alba. It also showed hypoglycemic effect by reducing glucose levels and lipid peroxidation and increasing insulin levels in rats with streptozotocin-induced diabetes mellitus.

Technology Process of Moracin M

There total 48 articles about Moracin M which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-(3,5-dimethoxyphenyl)-6-hydroxybenzofuran (134937-20-5) → moracin M (56317-21-6)

Guidance literature:

With aluminum (III) chloride; In chloroform; at 65 ℃; for 9h; Reagent/catalyst; Solvent; Temperature;

Reference yield: 92.0%

2-(3,5-dimethoxyphenyl)-6-methoxybenzofuran (73343-39-2) → moracin M (56317-21-6)

Guidance literature:

2-(3,5-dimethoxyphenyl)-6-methoxybenzofuran; With boron tribromide; In dichloromethane; at -78 - 25 ℃; for 24h; Schlenk technique; Inert atmosphere;

With water; In dichloromethane; Schlenk technique; Inert atmosphere; Cooling with ice;

DOI:10.1002/anie.202006542

Reference yield: 86.0%

1,3-bis(triisopropylsilyloxy)-5-(6-t-butyldiphenylsilyloxy-2-benzofuranyl)benzene (112768-55-5) → moracin M (56317-21-6)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; for 48h; Ambient temperature;

DOI:10.1016/S0040-4039(00)96171-9

upstream raw materials:

1,3-bis(triisopropylsilyloxy)-5-(6-t-butyldiphenylsilyloxy-2-benzofuranyl)benzene

2-(3,5-dimethoxyphenyl)-6-hydroxybenzofuran

C₃₆H₆₅N₂O₆PSi₃

2-(3,5-dibenzyloxyphenyl)-6-benzyloxybenzofuran

Downstream raw materials:

2-(3,5-dimethoxyphenyl)-6-methoxybenzofuran