7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID

Base Information

Chemical Name:7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID
CAS No.:67637-77-8
Molecular Formula:C11H11NO4S
Molecular Weight:267.30100
Hs Code.:
Mol file:67637-77-8.mol

Synonyms:7-(2-hydroxy-ethyl)-2-methyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid;7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID;

Suppliers and Price of 7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

American Custom Chemicals Corporation
7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO(2,3-B)PYRIDINE-5-CARBOXYLIC ACID 95.00%
5MG
$ 504.68

Total 0 raw suppliers

Chemical Property of 7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID

Chemical Property:

Vapor Pressure:1.29E-10mmHg at 25°C
Boiling Point:495oC at 760 mmHg
Flash Point:253.2oC
PSA：107.77000
Density:1.447g/cm3
LogP:1.45200

Purity/Quality:: 7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO(2,3-B)PYRIDINE-5-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID

There total 3 articles about 7-(3-HYDROXYPROPYL)-2-METHYL-4-OXO-4,7-DIHYDROTHIENO[2,3-B]PYRIDINE-5-CARBOXYLIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 55502-88-0
diethyl N-(5-methyl-2-thienyl)aminomethylenemalonate

: 67637-77-8
7-(2-hydroxy-ethyl)-2-methyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 3 steps

1: diphenyl ether / 0.5 h / Heating

2: aq. NaOH / 1 h / Heating

3: (i) K₂CO₃, DMF, (ii) /BRN= 878139/

With sodium hydroxide; In diphenylether;

Reference yield:

: 55503-12-3
2-methyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid ethyl ester

: 67637-77-8
7-(2-hydroxy-ethyl)-2-methyl-4-oxo-4,7-dihydro-thieno[2,3-b]pyridine-5-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / 1 h / Heating

2: (i) K₂CO₃, DMF, (ii) /BRN= 878139/

With sodium hydroxide;