6-(3-Chlorophenylamino)4-isopropyl-nicotinic acid

Base Information

Chemical Name:6-(3-Chlorophenylamino)4-isopropyl-nicotinic acid
CAS No.:676626-86-1
Molecular Formula:C15H15ClN2O2
Molecular Weight:290.749
Hs Code.:
DSSTox Substance ID:DTXSID701158013

Synonyms:6-(3-chlorophenylamino)4-isopropyl-nicotinic acid;SCHEMBL4648950;NAWRPXVSHPFPPJ-UHFFFAOYSA-N;DTXSID701158013;676626-86-1;6-(3chlorophenylamino)-4-isopropyl-nicotinic acid;6-(3-chlorophenylamino)-4-isopropyl-nicotinic acid;6-(3-chloro-phenylamino)-4-isopropyl-nicotinic acid;6-[(3-Chlorophenyl)amino]-4-(1-methylethyl)-3-pyridinecarboxylic acid

Suppliers and Price of 6-(3-Chlorophenylamino)4-isopropyl-nicotinic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-(3-Chlorophenylamino)4-isopropyl-nicotinic acid

Chemical Property:

XLogP3:4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:290.0822054
Heavy Atom Count:20
Complexity:338

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C1=CC(=NC=C1C(=O)O)NC2=CC(=CC=C2)Cl

Technology Process of 6-(3-Chlorophenylamino)4-isopropyl-nicotinic acid

There total 1 articles about 6-(3-Chlorophenylamino)4-isopropyl-nicotinic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 676626-86-1
6-(3-chloro-phenylamino)-4-isopropyl-nicotinic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 19 h / 0 - 20 °C

1.2: 1.5 h / -70 - 20 °C

2.1: 1.5 h / 120 °C

In tetrahydrofuran;

Reference yield:

: 676626-86-1
6-(3-chloro-phenylamino)-4-isopropyl-nicotinic acid

: 140-75-0
para-fluorobenzylamine

: 676993-23-0
6-(3-chlorophenylamino)-n-(4-fluorobenzyl)-4-isopropyl-nicotinamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
DOI:10.1016/j.bmcl.2008.10.118

Reference yield:

: 676626-86-1
6-(3-chloro-phenylamino)-4-isopropyl-nicotinic acid

: 2516-34-9
cyclobutylamine

: 676628-11-8
6-(3-chloro-phenylamino)-N-cyclobutyl-4-isopropyl-nicotinamide

Guidance literature:: With N-ethylmorpholine;; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In DMF (N,N-dimethyl-formamide);