Salicyluric acid

Base Information Edit

Chemical Name:Salicyluric acid
CAS No.:487-54-7
Molecular Formula:C9H9NO4
Molecular Weight:195.175
Hs Code.:29242998
European Community (EC) Number:207-661-6
NSC Number:524135,87566
UNII:5BR3P7J05U
DSSTox Substance ID:DTXSID70197592
Nikkaji Number:J54.010B
Wikipedia:Salicyluric_acid
Wikidata:Q2214314
Metabolomics Workbench ID:37456
ChEMBL ID:CHEMBL586
Mol file:487-54-7.mol

Synonyms:2-hydroxybenzoylglycine;N-(2-hydroxybenzoyl)glycine;N-(o-hydroxybenzoyl)glycine;o-hydroxyhippuric acid;salicylglycine;salicylurate;salicylurate, monosodium salt;salicyluric acid

Suppliers and Price of Salicyluric acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
2-Hydroxy hippuric acid
1g
$ 375.00

TRC
2-HydroxyHippuricAcid
5g
$ 190.00

SynQuest Laboratories
[(2-Hydroxybenzoyl)amino]acetic acid
250 mg
$ 29.00

SynQuest Laboratories
[(2-Hydroxybenzoyl)amino]acetic acid
1 g
$ 55.00

Sigma-Aldrich
o-Hydroxyhippuric acid analytical standard
50mg
$ 51.20

Medical Isotopes, Inc.
2-HydroxyhippuricAcid
12.5 g
$ 1880.00

Matrix Scientific
2-Hydroxyhippuric acid 97%
5g
$ 295.00

Matrix Scientific
2-Hydroxyhippuric acid 97%
1g
$ 72.00

Crysdot
2-(2-Hydroxybenzamido)aceticacid 95+%
10g
$ 415.00

Atlantic Research Chemicals
2-Hydroxyhippuricacid 95%
10gm:
$ 318.11

Total 47 raw suppliers

Chemical Property of Salicyluric acid Edit

Chemical Property:

Appearance/Colour:light gray crystalline powder
Vapor Pressure:2.08E-10mmHg at 25°C
Melting Point:164-169 °C
Refractive Index:1.5700 (estimate)
Boiling Point:489.79 °C at 760 mmHg
PKA:3.68±0.10(Predicted)
Flash Point:250.016 °C
PSA：86.63000
Density:1.401 g/cm³
LogP:0.59750
Storage Temp.:Store at 0°C
Solubility.:DMSO (Slightly), Methanol (Slightly)
XLogP3:0.9
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:195.05315777
Heavy Atom Count:14
Complexity:229

Purity/Quality:

99%, ^*data from raw suppliers

2-Hydroxy hippuric acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 24/25-36/37/39-27-26

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(=O)NCC(=O)O)O
Description Salicyluric acid is an N-acylglycine in which the acyl group is specified as 2-hydroxybenzoyl. It has a role as a uremic toxin and a human xenobiotic metabolite. It is a N-acylglycine and a secondary carboxamide. It is functionally related to a glycine. It is a conjugate acid of a salicylurate.
Uses Metabolite of Salicylic Acid (S088125). 2-Hydroxyhippuric acid is a phenol marker. Can be associated with dietary intake or bacterial overgrowth. Indicators of Detoxification: A conjugate of the amino acid glycine and hydroxybenzoic acid (salicylic acid). Intake of aspirin (salicylates) or the growth of salicylate-producing gastrointestinal bacteria may elevate levels. Also increased after the ingestion of the artificial sweetener aspartame (Nutrasweet).

Technology Process of Salicyluric acid

There total 27 articles about Salicyluric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 178633-73-3
(2-Hydroxy-benzoylamino)-acetic acid benzyl ester

: 487-54-7
Salicyluric acid

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; 0 deg C, then 0oom temp., overnight;
DOI:10.1002/hlca.19970800312