4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile

Base Information

Chemical Name:4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile
CAS No.:67677-96-7
Molecular Formula:C₂₃H₁₆N₄
Molecular Weight:348.407
Hs Code.:
DSSTox Substance ID:DTXSID20494386
Wikidata:Q82341704

Synonyms:67677-96-7;4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile;2,4-diphenyl-6-(phenylamino)pyrimidine-5-carbonitrile;DTXSID20494386

Suppliers and Price of 4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile

Chemical Property:

XLogP3:5.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:348.137496527
Heavy Atom Count:27
Complexity:494

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=C(C(=NC(=N2)C3=CC=CC=C3)NC4=CC=CC=C4)C#N

Technology Process of 4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile

There total 2 articles about 4-Anilino-2,6-diphenylpyrimidine-5-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 737-53-1
4-chloro-2,6-diphenylpyrimidine-5-carbonyltrile

: 62-53-3
aniline

: 67677-96-7
4-anilino-2,6-diphenyl-pyrimidine-5-carbonitrile

Guidance literature:: In 1,4-dioxane; for 2h; Heating;

Reference yield:

: 737-54-2
6-oxo-2,4-diphenyl-1,6-dihydro-pyrimidine-5-carbonitrile

: 67677-96-7
4-anilino-2,6-diphenyl-pyrimidine-5-carbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 87 percent / phosphorus oxychloride / dioxane / 1 h / Heating

2: 79 percent / dioxane / 2 h / Heating

With trichlorophosphate; In 1,4-dioxane;