6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile

Base Information

Chemical Name:6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile
CAS No.:67720-43-8
Molecular Formula:C14H10N4O
Molecular Weight:250.26
Hs Code.:
DSSTox Substance ID:DTXSID301151865
Nikkaji Number:J2.526.453C

Synonyms:DTXSID301151865;AKOS024284484;67720-43-8;6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile

Suppliers and Price of 6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile

Chemical Property:

XLogP3:1.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:250.08546096
Heavy Atom Count:19
Complexity:573

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C2=C(C(=O)NC(=C2C#N)N)C#N

Technology Process of 6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile

There total 3 articles about 6-Amino-1,2-dihydro-4-(4-methylphenyl)-2-oxo-3,5-pyridinedicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 79388-05-9
1,6-diamino-4-(4-methylphenyl)-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile

: 67720-43-8
6-amino-1,2-dihydro-2-oxo-4-p-tolylpyridine-3,5-dicarbonitrile

Guidance literature:: With nitrosylsulfuric acid; In acetic acid; Ambient temperature;
DOI:10.1055/s-1981-29512

Reference yield: 45.0%

: 104-87-0
4-methyl-benzaldehyde

: 109-77-3
malononitrile

: 67720-43-8
6-amino-1,2-dihydro-2-oxo-4-p-tolylpyridine-3,5-dicarbonitrile

Guidance literature:: With sodium hydroxide; In water; at 100 ℃; for 0.05h; Irradiation; Microwave;
DOI:10.1002/jhet.5570440533

Reference yield:

: 2826-25-7
2-(4-methylbenzylidene)malononitrile

: 67720-43-8
6-amino-1,2-dihydro-2-oxo-4-p-tolylpyridine-3,5-dicarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / piperidine / ethanol / Ambient temperature

2: 97 percent / nitrosylsulfuric acid / acetic acid / Ambient temperature

With piperidine; nitrosylsulfuric acid; In ethanol; acetic acid;
DOI:10.1055/s-1981-29512