79388-05-9Relevant articles and documents
Pyrido triazin-nucleus synthesis and theoretical studies: 2,3,6-trioxo-8-aryl-1,3,4,6-tetrahydro-]2H[pyrido]1,2-b] [1,2,4[triazin-7,9-dicarbonitryl derivatives
Darehkordi, Ali,Mohammadi, Marziyeh,Nejadkhorasani, Farzaneh,Tahmasby, Maryam
, (2020/08/13)
An efficient method for the synthesis of potentially biologically [2H]-pyrido [1,2-b]1,2,4-triazines derivatives is described via reaction of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives with oxalyl chloride in DMF in the presence of pyridine as a base. The intramolecular hydrogen bonding (IMHB) interactions have been investigated at M06-2X/6-311++G(d,p) level of theory. The eight compounds (5a-h) characterized by geometries and energies. The Natural bond orbital (NBO) and quantum theory of atoms in molecules (QTAIM) were performed to explore the nature of the hydrogen-bonding interactions in these compounds. The IMHB formed between the C[dbnd]O and N[sbnd]H groups. The theoretical calculations showed that the IMHB strength increases in the presence of electron-donor substituents. An opposite behavior was observed for electron-acceptor substituents.
Convenient Synthesis of New Boric Acid Catalyzed 1,2,4-Triazolopyridinone Derivatives and an Investigation of their Optical Properties
Darehkordi, Ali,Hosseini, Maryam,Rahmani, Fariba
, p. 1306 - 1311 (2019/02/19)
Syntheses of fused heterobicyclic systems containing 1,2,4-triazolopyridinone moieties were accomplished by heterocyclization of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitriles and ninhydrin in ethanol and in the presence of boric acid as a catalyst in 30?min at room temperature. All compounds have been screened for their photophysical properties. Results showed that all compounds exhibit near infrared emissions at 876?nm.
Dipyrido[1,2-b:3′,4′-e][1,2,4]triazine Scaffolds from Pentafluoropyridine
Ranjbar-Karimi, Reza,Darehkordi, Ali,Bahadornia, Fahimeh,Poorfreidoni, Alireza
, p. 2516 - 2521 (2018/09/21)
Annelation reaction between pentafluoropyridine and diaminodihydro substituted pyridine derivatives gave dipyrido[1,2-b:3′,4′-e][1,2,4]triazine systems as major products arising from the initial nucleophilic substitution of more nucleophilic N-amino group
A three component one-pot synthesis of N-amino-2-pyridone derivatives catalyzed by KF-Al2O3
Kshiar,Shangpliang,Myrboh
supporting information, p. 1816 - 1827 (2018/06/25)
Synthesis of 1,6-diamino-4-phenyl-3,5-dicyano-2-pyridone derivatives via a one-pot, three-component reaction of aryl aldehydes, malononitrile, and cyanoacetic hydrazide at room temperature using KF-Al2O3 as a recyclable catalyst have been developed. The reaction proceeds through the initial Knoevenagel condensation between aldehyde and malononitrile in the presence of KF-Al2O3 to form the benzylidene derivative which then undergoes Michael addition with cyanoacetic hydrazide followed by intramolecular cyclization of the resulting intermediate to produce the N-amino-2-pyridones in good to excellent yields. The structure of the synthesized compounds were characterized and established on the basis of their spectral data analysis and single-crystal XRD analysis.
A comparative screening of the catalytic activity of nanocrystalline MIIZr4(PO4)6 ceramics in the one-pot synthesis of 1,6-diamino-4-aryl-2-oxo-1,2-dihydropyridine-3,5-dicarbonitrile derivatives
Safaei-Ghomi, Javad,Shahbazi-Alavi, Hossein,Ziarati, Abolfazl
, p. 91 - 101 (2017/01/14)
A four-component reaction of hydrazine hydrate, ethyl cyanoacetate, malononitrile, and aromatic aldehydes was achieved in the presence of nanocrystalline MIIZr4(PO4)6 ceramics (MII: Mn, Fe, Co, Ni, Cu, Zn, Cd) as heterogeneous catalysts to produce N-amino-2-pyridones. The reactions were performed in the presence of different catalysts, and it is observed that CdZr4(PO4)6 nanocrystallines are the best catalysts among those examined. Atom economy, excellent yields in short times, high catalytic activity, recycling of catalyst, and environmental benignity are some of the important features of this protocol.
An efficient method for the synthesis of N-amino-2-pyridones using reusable catalyst ZnO nanoparticles
Safaei-Ghomi, Javad,Saberi-Moghadam, Mohammad Reza,Shahbazi-Alavi, Hossein,Asgari-Kheirabadi, Mehrnoosh
, p. 583 - 585 (2015/01/08)
A concise and highly efficient protocol for the synthesis of N.amino-2-pyridones has been developed by a four-component coupling of hydrazine hydrate, ethyl cyanoacetate, malononitrile and aromatic aldehydes in the presence of ZnO nanoparticles under mild conditions. The key advantages of this process are using an inexpensive and reusable catalyst, easy work.up and excellent yields.
