Acetamide, N-(2-(acetyloxy)-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)-

Base Information

• Chemical Name: Acetamide, N-(2-(acetyloxy)-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)-
• CAS No.: 70153-33-2
• Molecular Formula: C20H25NO4
• Molecular Weight: 343.4168
• DSSTox Substance ID: DTXSID80990399
• Mol file: 70153-33-2.mol

Synonyms:70153-33-2;Acetamide, N-(2-(acetyloxy)-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)-;SCHEMBL9332855;DTXSID80990399;1-(N-ISOPROPYLACETAMIDO)-3-(NAPHTHALEN-1-YLOXY)PROPAN-2-YL ACETATE;1-(naphthalen-1-yloxy)-3-[N-(propan-2-yl)acetamido]propan-2-yl acetate;1-[Acetyl(propan-2-yl)amino]-3-[(naphthalen-1-yl)oxy]propan-2-yl acetate

Chemical Property of Acetamide, N-(2-(acetyloxy)-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)-

Chemical Property:

• Vapor Pressure: 2.87E-10mmHg at 25°C
• Boiling Point: 503.6°Cat760mmHg
• Flash Point: 258.3°C
• Density: 1.126g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 343.17835828
• Heavy Atom Count: 25
• Complexity: 451

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N(CC(COC1=CC=CC2=CC=CC=C21)OC(=O)C)C(=O)C

Technology Process of Acetamide, N-(2-(acetyloxy)-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)-

There total 6 articles about Acetamide, N-(2-(acetyloxy)-3-(1-naphthalenyloxy)propyl)-N-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

acetic anhydride (108-24-7) + Inderal (318-98-9) → N-[2-acetyloxy-3-(1-naphthalenyloxy)propyl]-N-(1-methylethyl)acetamide (70153-33-2)

Guidance literature:

With triethylamine; In chloroform; at 20 ℃; for 20h;

DOI:10.1016/j.lfs.2005.04.033

Reference yield: 54.0%

acetic anhydride (108-24-7) + propranolol (525-66-6) → N-[2-acetyloxy-3-(1-naphthalenyloxy)propyl]-N-(1-methylethyl)acetamide (70153-33-2)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 4h;

DOI:10.1016/j.tetasy.2016.10.003

Reference yield:

acetic anhydride (108-24-7) + propranolol (525-66-6) → N-[2-hydroxy-3-(1-naphthalenyloxy)propyl]-N-(1-methylethyl)acetamide (2007-11-6) + 1-(isopropylamino)-3-(naphthalen-1-yloxy)propan-2-yl acetate (129459-75-2) + N-[2-acetyloxy-3-(1-naphthalenyloxy)propyl]-N-(1-methylethyl)acetamide (70153-33-2)

Guidance literature:

With sodium hydrogencarbonate; In chloroform; at 45 ℃; for 24h;

DOI:10.1155/2020/9597426

upstream raw materials:

acetyl chloride

propranolol

acetic anhydride

Inderal

Downstream raw materials:

N-[2-hydroxy-3-(1-naphthalenyloxy)propyl]-N-(1-methylethyl)acetamide