3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)-

Base Information

Chemical Name:3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)-
CAS No.:67766-85-2
Molecular Formula:C12H8N2O3
Molecular Weight:228.20400
Hs Code.:
DSSTox Substance ID:DTXSID40425399
Wikidata:Q82238247
ChEMBL ID:CHEMBL5014569

Synonyms:67766-85-2;5-(1H-indol-3-yl)-1,2-oxazole-3-carboxylic acid;5-(1H-INDOL-3-YL)ISOXAZOLE-3-CARBOXYLIC ACID;3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)-;Oprea1_178097;CHEMBL5014569;DTXSID40425399;MFCD00450882;STK365546;AKOS003673452;LS-04011;5-(3-indolyl)isoxazole-3-carboxylic acid;CS-0270258;EN300-1870851;5-(1H-INDOL-3-YL)ISOXAZOLE-3-CARBOXYLICACID

Suppliers and Price of 3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
5-(1H-Indol-3-yl)isoxazole-3-carboxylic acid
500mg
$ 394.00

Crysdot
5-(1H-Indol-3-yl)isoxazole-3-carboxylicacid 97%
1g
$ 415.00

Chemenu
5-(1H-Indol-3-yl)isoxazole-3-carboxylicacid 95%+
1g
$ 392.00

American Custom Chemicals Corporation
3-ISOXAZOLECARBOXYLIC ACID, 5-(1H-INDOL-3-YL)- 95.00%
5MG
$ 503.87

Total 8 raw suppliers

Chemical Property of 3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)-

Chemical Property:

PSA：78.59000
LogP:0.93750
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:228.05349212
Heavy Atom Count:17
Complexity:310

Purity/Quality:

98%min ^*data from raw suppliers

5-(1H-Indol-3-yl)isoxazole-3-carboxylic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)C3=CC(=NO3)C(=O)O

Technology Process of 3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)-

There total 2 articles about 3-Isoxazolecarboxylic acid, 5-(1H-indol-3-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67766-84-1
ethyl 5-(1H-indol-3-yl)isoxazole-3-carboxylate

: 67766-85-2
5-indol-3-yl-isoxazole-3-carboxylic acid

Guidance literature:: With sodium carbonate; In ethanol; Heating;
DOI:10.1007/BF00471644

Reference yield:

: 51842-50-3
ethyl 4-(1H-indol-3-yl)-2,4-dioxobutanoate

: 67766-85-2
5-indol-3-yl-isoxazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: NH₂OH*HCl, Py / ethanol / Heating

2: aq. Na₂CO₃ / ethanol / Heating

With pyridine; hydroxylamine hydrochloride; sodium carbonate; In ethanol;
DOI:10.1007/BF00471644