Lofentanil oxalate

Base Information

Chemical Name:Lofentanil oxalate
CAS No.:61380-41-4
Molecular Formula:C₂H₂O₄*C₂₅H₃₂N₂O₃
Molecular Weight:498.576
Hs Code.:
European Community (EC) Number:262-750-7
UNII:6C1599T3OQ
DSSTox Substance ID:DTXSID10976924
Wikidata:Q27264468
NCI Thesaurus Code:C80584
Mol file:61380-41-4.mol

Synonyms:lofentanil;lofentanil oxalate;lofentanil oxalate, (cis-(+))-isomer;lofentanil oxalate, (cis-(-))-isomer;lofentanil, (cis)-(+)-isomer;lofentanil, cis-(+-)-isomer;lofentanil, cis-(-)-isomer;lofentanil, trans-(+-)-isomer;lofentanyl;R 34995

Suppliers and Price of Lofentanil oxalate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
LOFENTANIL OXALATE 95.00%
5MG
$ 500.73

Total 4 raw suppliers

Chemical Property of Lofentanil oxalate

Chemical Property:

Vapor Pressure:1.08E-10mmHg at 25°C
Melting Point:177°
Boiling Point:514.4°C at 760 mmHg
Flash Point:264.9°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:9
Exact Mass:498.23660143
Heavy Atom Count:36
Complexity:640

Purity/Quality:

99% ^*data from raw suppliers

LOFENTANIL OXALATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2C)CCC3=CC=CC=C3)C(=O)OC.C(=O)(C(=O)O)O
Isomeric SMILES:CCC(=O)N(C1=CC=CC=C1)[C@@]2(CCN(C[C@@H]2C)CCC3=CC=CC=C3)C(=O)OC.C(=O)(C(=O)O)O
Uses Analgesic (narcotic). Controlled Substance.

Technology Process of Lofentanil oxalate

There total 5 articles about Lofentanil oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 345652-52-0
cis methyl 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylate

: 67-66-3,8013-54-5
chloroform

: 802294-64-0,79-09-4
propionic acid

: 61087-48-7,61087-50-1,61380-39-0,61380-41-4,73025-44-2,73025-45-3,73025-48-6,73025-49-7
trans-methyl 3-methyl-4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate ethanedioate

Guidance literature:: In water; isopropyl alcohol;

Reference yield:

: cis 3-methyl-4-(phenylamino)-1-(2-phenylethyl)-4-piperidinecarboxylic acid sodium salt

: 61087-48-7,61087-50-1,61380-39-0,61380-41-4,73025-44-2,73025-45-3,73025-48-6,73025-49-7
trans-methyl 3-methyl-4-[N-(1-oxopropyl)-N-phenylamino]-1-(2-phenylethyl)-4-piperidinecarboxylate ethanedioate

Guidance literature:: Multi-step reaction with 2 steps

1: N,N,N,N,N,N-hexamethylphosphoric triamide; ice-water; water

2: water; isopropyl alcohol

In N,N,N,N,N,N-hexamethylphosphoric triamide; ice-water; water; isopropyl alcohol;