Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-, (2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester

Base Information

Chemical Name:Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-, (2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester
CAS No.:679003-43-1
Molecular Formula:C43H80O7SSi
Molecular Weight:769.255
Hs Code.:

Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-,
(2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec
yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester

Synonyms:

Suppliers and Price of Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-, (2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-, (2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-, (2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester

There total 3 articles about Benzenesulfonic acid, 2,4,6-tris(1-methylethyl)-, (2S,5R)-5-[(2S,5S)-5-[(1R)-1-[[(1,1-dimethylethyl)dimethylsilyl]oxy]tridec yl]tetrahydro-2-furanyl]-2,5-dihydroxypentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 6553-96-4
2,4,6-triisopropylphenylsulfonyl chloride

: 679003-36-2
(2S,5R,6S,9S,10R)-10-(tert-butyldimethylsilyloxy)-6,9-epoxydocosane-1,2,5-triol

: 679003-43-1
(2S,5R,6S,9S,10R)-10-(tert-butyldimethylsilyloxy)-2,5-dihydroxy-6,9-epoxydocosanyl 2,4,6-triisopropylbenzenesulfonate

Guidance literature:: In pyridine; dichloromethane; at 20 ℃; for 21h;
DOI:10.1002/chem.200305459

Reference yield:

: 636596-71-9
(2S,5S)-5-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-tridecyl]-tetrahydro-furan-2-carbaldehyde

: 679003-43-1
(2S,5R,6S,9S,10R)-10-(tert-butyldimethylsilyloxy)-2,5-dihydroxy-6,9-epoxydocosanyl 2,4,6-triisopropylbenzenesulfonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: Zn(OTf)2; (1S,2R)-N-methylephedrine; Et₃N / toluene / 0.25 h / 20 °C

1.2: toluene / 19 h / 20 °C

2.1: 83 percent / H₂ / Pd/C / ethyl acetate / 19 h / 20 °C

3.1: 73 percent / CH₂Cl₂; pyridine / 21 h / 20 °C

With (1S,2R)-(+)-N-methylephedrine; hydrogen; zinc trifluoromethanesulfonate; triethylamine; palladium on activated charcoal; In pyridine; dichloromethane; ethyl acetate; toluene;
DOI:10.1002/chem.200305459

Reference yield:

: 679003-31-7
(2RS,4S)-4-[(3'R,4'S,7'S,8'R)-8'-(tert-butyldimethylsilyloxy)-3'-hydroxy-4',7'-epoxy-1'-icosynyl]-2-phenyl-1,3-dioxolane

: 679003-43-1
(2S,5R,6S,9S,10R)-10-(tert-butyldimethylsilyloxy)-2,5-dihydroxy-6,9-epoxydocosanyl 2,4,6-triisopropylbenzenesulfonate

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / H₂ / Pd/C / ethyl acetate / 19 h / 20 °C

2: 73 percent / CH₂Cl₂; pyridine / 21 h / 20 °C

With hydrogen; palladium on activated charcoal; In pyridine; dichloromethane; ethyl acetate;
DOI:10.1002/chem.200305459