1,5-DIMETHYL-1H-[1,2,4]TRIAZOL-3-YLAMINE

Base Information

• Chemical Name: 1,5-DIMETHYL-1H-[1,2,4]TRIAZOL-3-YLAMINE
• CAS No.: 34776-19-7
• Molecular Formula: C4H8N4
• Molecular Weight: 112.134
• Hs Code.: 2933990090
• Mol file: 34776-19-7.mol

Synonyms:dimethyl-1,2,4-triazol-3-amine;1,5-Dimethyl-3-amino-1,2,4-triazol;3-amino-1,5-dimethyl-1,2,4-triazole;1,5-dimethyl-1H-1,2,4-triazol-3-amine;3-amino-1,5-dimethyl-1H-1,2,4-triazole;1,5-dimethyl-3-amino-1,2,4-triazole;

Chemical Property of 1,5-DIMETHYL-1H-[1,2,4]TRIAZOL-3-YLAMINE

Chemical Property:

• Vapor Pressure: 0.0011mmHg at 25°C
• Melting Point: 187-189 °C(Solv: benzene (71-43-2))
• Boiling Point: 300.7°Cat760mmHg
• PKA: 5.53±0.10(Predicted)
• Flash Point: 135.7°C
• PSA: 56.73000
• Density: 1.34g/cm³
• LogP: 0.28690

Purity/Quality:

98%min ^*data from raw suppliers

1,5-Dimethyl-1H-[1,2,4]triazol-3-ylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,5-DIMETHYL-1H-[1,2,4]TRIAZOL-3-YLAMINE

There total 2 articles about 1,5-DIMETHYL-1H-[1,2,4]TRIAZOL-3-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

methylhydrazine (60-34-4) + C5H8N2S → 3-amino-1,5-dimethyl-1H-1,2,4-triazole (34776-19-7)

Guidance literature:

In chloroform; Heating;

DOI:10.1002/hlca.19830660416

Reference yield:

→ 3-amino-1,5-dimethyl-1H-1,2,4-triazole (34776-19-7)

Guidance literature:

Verb. 1, Methylhydrazin (neben Hauptkomponente 6);

DOI:10.1021/jo00924a015

Reference yield: 11.0%

5-bromo-2-(4-methyl-1H-imidazol-1-yl)benzonitrile (870837-41-5) + 3-amino-1,5-dimethyl-1H-1,2,4-triazole (34776-19-7) → 5-(1,5-dimethyl-1H-[1,2,4]triazol-3-ylamino)-2-(4-methyl-imidazol-1-yl)-benzonitrile (1225444-48-3)

Guidance literature:

With sodium phenoxide; tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 80 ℃; for 2h; Inert atmosphere;

upstream raw materials:

methylhydrazine

Downstream raw materials:

5-(1,5-dimethyl-1H-[1,2,4]triazol-3-ylamino)-2-(4-methyl-imidazol-1-yl)-benzonitrile

Refernces

• 1、 Kristinsson, Haukur,Winkler, Tammo. "113. Notiz ueber die Reaktion von Methylhydrazin mit N-Cyano-azomethinen. Abhaengigkeit des Reaktionsverlaufs von der Natur der Abgangsgruppe". . p. 1129 - 1133. Retrieved 2007/10/02.