2,6-DIHYDROXY-4-METHYLBENZALDEHYDE

Base Information

• Chemical Name: 2,6-DIHYDROXY-4-METHYLBENZALDEHYDE
• CAS No.: 526-37-4
• Molecular Formula: C8H8 O3
• Molecular Weight: 152.15
• Hs Code.: 2912499000
• Mol file: 526-37-4.mol

Synonyms:Atranol(6CI); g-Resorcylaldehyde, 4-methyl-(7CI,8CI); 2,6-Dihydroxy-4-methylbenzaldehyde;2,6-Dihydroxy-p-methylbenzaldehyde; 4-Methyl-2,6-dihydroxybenzaldehyde;p-Orsellinaldehyde

Chemical Property of 2,6-DIHYDROXY-4-METHYLBENZALDEHYDE

Chemical Property:

• Vapor Pressure: 0.0155mmHg at 25°C
• Melting Point: 123.5-124 °C
• Boiling Point: 248.3°Cat760mmHg
• PKA: 7.77±0.15(Predicted)
• Flash Point: 118.2°C
• PSA: 57.53000
• Density: 1.331g/cm³
• LogP: 1.21870
• Storage Temp.: 2-8°C
• Solubility.: Actone (Slightly), DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

2,6-Dihydroxy-4-methylbenzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 1941881
• Hazard Codes: Xi
• Statements: 36/38-43
• Safety Statements: 26-36/37

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,6-Dihydroxy-4-methylbenzaldehyde is used in process for converting Atranol and its derivatives into Hydrosoluble compounds.

Technology Process of 2,6-DIHYDROXY-4-METHYLBENZALDEHYDE

There total 32 articles about 2,6-DIHYDROXY-4-METHYLBENZALDEHYDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2,6-bis(methoxymethyloxy)-4-methylbenzaldehyde (121287-34-1) → atranol (526-37-4)

Guidance literature:

With acetyl chloride; In methanol; at 18 ℃; for 20h;

DOI:10.1080/00304940509354959

Reference yield: 81.0%

acide formyl-3-dihydroxy-2,4-methyl-6-benzoique (479-25-4) → atranol (526-37-4)

Guidance literature:

With copper(I) oxide; [2,2]bipyridinyl; In diethylene glycol dimethyl ether; for 9h; Heating;

DOI:10.1002/hlca.19890720524

Reference yield: 50.0%

2,6-bis(ethoxymethoxy)-4-methylbenzaldehyde → atranol (526-37-4)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; at 20 ℃;

upstream raw materials:

fumarprotocetraric acid

salazinic acid

2,6-dimethoxy-4-methylbenzaldehyde

atranorin

Downstream raw materials:

orcinol

2,5-dimethyl-1,3-benzenediol

2,6-dihydroxy-4-methyl-benzoic acid

2,6-dimethoxy-4-methylbenzaldehyde