lyxoflavin 5'-monophosphate

Base Information

• Chemical Name: lyxoflavin 5'-monophosphate
• CAS No.: 53860-75-6
• Molecular Formula: C₁₇H₂₁N₄O₉P
• Molecular Weight: 456.349
• Mol file: 53860-75-6.mol

Synonyms:lyxoflavin 5'-monophosphate

Chemical Property of lyxoflavin 5'-monophosphate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of lyxoflavin 5'-monophosphate

There total 7 articles about lyxoflavin 5'-monophosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-amino-o-xylene (95-64-7) → O5'-phosphono-riboflavin (146-17-8,987-55-3,26193-20-4,33210-87-6,34469-63-1,53860-75-6,123052-26-6,69680-01-9)

Guidance literature:

Multi-step reaction with 4 steps

1.1: sodium cyanoborohydride / methanol / 48 h / Reflux

2.1: hydrogenchloride / water / 0.17 h / 0 °C

2.2: 0.5 h / 0 °C

3.1: butan-1-ol; acetic acid / 5 h / Reflux

4.1: ATP; 3-(N-morpholino)propanesulfonic acid; riboflavin kinase; magnesium chloride / aq. buffer / 12 h / 30 °C / pH 7.9 / Enzymatic reaction

With hydrogenchloride; 3-(N-morpholino)propanesulfonic acid; riboflavin kinase; sodium cyanoborohydride; ATP; magnesium chloride; In methanol; water; acetic acid; butan-1-ol;

DOI:10.1021/acs.joc.6b00640

Reference yield:

riboflavin (83-88-5,42880-33-1) → O5'-phosphono-riboflavin (146-17-8,987-55-3,26193-20-4,33210-87-6,34469-63-1,53860-75-6,123052-26-6,69680-01-9)

Guidance literature:

With trichlorophosphate; In water;

Reference yield:

riboflavin (83-88-5,482-11-1,482-12-2,3687-62-5,5978-87-0,13123-37-0,33210-89-8,35919-91-6,53187-51-2,53187-52-3,135681-43-5,42880-33-1) → O5'-phosphono-riboflavin (146-17-8,987-55-3,26193-20-4,33210-87-6,34469-63-1,53860-75-6,123052-26-6,69680-01-9)

Guidance literature:

With 3-(N-morpholino)propanesulfonic acid; riboflavin kinase; ATP; magnesium chloride; In aq. buffer; at 30 ℃; for 12h; pH=7.9; regiospecific reaction; Enzymatic reaction;

DOI:10.1021/acs.joc.6b00640

upstream raw materials:

riboflavin

4-amino-o-xylene

D-ribose

N-ribityl-3,4-dimethylaniline

Refernces

• 1、 -. "Preparation of riboflavin 5'-phosphate (FMN) and its sodium salt in a lactone". . . Retrieved 2008/06/13.