L-Serine, N-[(3,5-difluorophenyl)acetyl]-, methyl ester

Base Information

Chemical Name:L-Serine, N-[(3,5-difluorophenyl)acetyl]-, methyl ester
CAS No.:680230-09-5
Molecular Formula:C12H13F2NO4
Molecular Weight:273.236
Hs Code.:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of L-Serine, N-[(3,5-difluorophenyl)acetyl]-, methyl ester

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Technology Process of L-Serine, N-[(3,5-difluorophenyl)acetyl]-, methyl ester

There total 2 articles about L-Serine, N-[(3,5-difluorophenyl)acetyl]-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 5680-80-8
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

: 680230-09-5
N-[(3,5-difluorophenyl)acetyl]-L-serine methyl ester

Guidance literature:: 3,5-difluorophenyl acetic acid; With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 ℃; for 0.25h;

methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride; With 4-methyl-morpholine; In dichloromethane; at 0 - 25 ℃; for 3h;

Reference yield: 76.0%

: 5680-80-8
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

: 105184-38-1
3,5-difluorophenyl acetic acid

: 680230-09-5
N-[(3,5-difluorophenyl)acetyl]-L-serine methyl ester

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 0 - 20 ℃; for 3h;