Technology Process of Benzoic acid,
5-(acetylamino)-2-(3,3-diethyl-1-triazenyl)-4-[(trimethylsilyl)ethynyl]-,
octyl ester
There total 11 articles about Benzoic acid,
5-(acetylamino)-2-(3,3-diethyl-1-triazenyl)-4-[(trimethylsilyl)ethynyl]-,
octyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine;
at 40 ℃;
for 12h;
DOI:10.1021/ja039416d
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 78.3 percent / ICl; AcOH / 12 h
2.1: 93.8 percent / H2SO4 / CH2Cl2 / 1 h / 20 °C
3.1: 84.8 percent / AcOH / Fe / ethanol / 2 h / Heating
4.1: aq. NaNO2; aq. HCl / acetonitrile / 0.5 h / 0 °C
4.2: 86.2 percent / K2CO3 / acetonitrile; H2O / 0 - 20 °C
5.1: 93.8 percent / aq. NaOH / methanol / 0.5 h / Heating
6.1: 85.3 percent / DCC; DMAP / CH2Cl2 / 48 h / 20 °C
7.1: 93.8 percent / Pd(PPh3)2Cl2; CuI; Et3N / 12 h / 40 °C
With
hydrogenchloride; dmap; bis-triphenylphosphine-palladium(II) chloride; sodium hydroxide; copper(l) iodide; sulfuric acid; Iodine monochloride; acetic acid; triethylamine; dicyclohexyl-carbodiimide; sodium nitrite;
iron;
In
methanol; ethanol; dichloromethane; acetonitrile;
7.1: Sonogashira coupling;
DOI:10.1021/ja039416d
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: 92.3 percent / H2SO4 / methanol / 0.5 h / Heating
2.1: 78.3 percent / ICl; AcOH / 12 h
3.1: 93.8 percent / H2SO4 / CH2Cl2 / 1 h / 20 °C
4.1: 84.8 percent / AcOH / Fe / ethanol / 2 h / Heating
5.1: aq. NaNO2; aq. HCl / acetonitrile / 0.5 h / 0 °C
5.2: 86.2 percent / K2CO3 / acetonitrile; H2O / 0 - 20 °C
6.1: 93.8 percent / aq. NaOH / methanol / 0.5 h / Heating
7.1: 85.3 percent / DCC; DMAP / CH2Cl2 / 48 h / 20 °C
8.1: 93.8 percent / Pd(PPh3)2Cl2; CuI; Et3N / 12 h / 40 °C
With
hydrogenchloride; dmap; bis-triphenylphosphine-palladium(II) chloride; sodium hydroxide; copper(l) iodide; sulfuric acid; Iodine monochloride; acetic acid; triethylamine; dicyclohexyl-carbodiimide; sodium nitrite;
iron;
In
methanol; ethanol; dichloromethane; acetonitrile;
8.1: Sonogashira coupling;
DOI:10.1021/ja039416d
