3,5-Pyridinedicarboxylic acid, bis[2-[(4-methylphenyl)sulfonyl]hydrazide]

Base Information

• Chemical Name: 3,5-Pyridinedicarboxylic acid, bis[2-[(4-methylphenyl)sulfonyl]hydrazide]
• CAS No.: 681129-08-8
• Molecular Formula: C21H21N5O6S2
• Molecular Weight: 503.56
• Mol file: 681129-08-8.mol

Synonyms:

Chemical Property of 3,5-Pyridinedicarboxylic acid, bis[2-[(4-methylphenyl)sulfonyl]hydrazide]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3,5-Pyridinedicarboxylic acid, bis[2-[(4-methylphenyl)sulfonyl]hydrazide]

There total 2 articles about 3,5-Pyridinedicarboxylic acid, bis[2-[(4-methylphenyl)sulfonyl]hydrazide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

pyridine-3,5-dicarbonyl dichloride (15074-61-0) + toluene-4-sulfonic acid hydrazide (1576-35-8) → C21H21N5O6S2 (681129-08-8)

Guidance literature:

With pyridine; In dichloromethane; at 40 ℃; for 4h;

DOI:10.1021/ol049912m

Reference yield:

3,5-Pyridinedicarboxylic acid (499-81-0) → C21H21N5O6S2 (681129-08-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / SOCl₂; DMF / toluene / 1 h / 110 °C

2: 82 percent / pyridine / CH₂Cl₂ / 4 h / 40 °C

With pyridine; thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; toluene;

DOI:10.1021/ol049912m

Reference yield: 25.0%

C21H21N5O6S2 (681129-08-8) → pyridine-3,5-bis-carbaldehyde (6221-04-1)

Guidance literature:

With potassium carbonate; In ethylene glycol; at 150 ℃; for 0.0833333h;

DOI:10.1021/ol049912m

upstream raw materials:

pyridine-3,5-dicarbonyl dichloride

toluene-4-sulfonic acid hydrazide

3,5-Pyridinedicarboxylic acid

Downstream raw materials:

pyridine-3,5-bis-carbaldehyde

Refernces