N-Benzyloxycarbonyl-leucyl-leucyl-phenylalaninal

Base Information

Chemical Name:N-Benzyloxycarbonyl-leucyl-leucyl-phenylalaninal
CAS No.:143839-79-6
Molecular Formula:C₂₉H₃₉N₃O₅
Molecular Weight:509.646
Hs Code.:
DSSTox Substance ID:DTXSID70932122
Mol file:143839-79-6.mol

Synonyms:Boc-Leu-Leu-Phe-CHO;N-benzyloxycarbonyl-leucyl-leucyl-phenylalaninal;Z-Leu-Leu-Phe-al;Z-LLF-CHO

Suppliers and Price of N-Benzyloxycarbonyl-leucyl-leucyl-phenylalaninal

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of N-Benzyloxycarbonyl-leucyl-leucyl-phenylalaninal

Chemical Property:

Vapor Pressure:2.84E-17mmHg at 25°C
Boiling Point:659.6°Cat760mmHg
PKA:11.14±0.46(Predicted)
Flash Point:352.7°C
PSA：124.07000
Density:1.122g/cm³
LogP:5.66980
XLogP3:5.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:15
Exact Mass:509.28897135
Heavy Atom Count:37
Complexity:714

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(=O)C(CC(C)C)NC(=O)OCC1=CC=CC=C1)NC(CC2=CC=CC=C2)C=O
Isomeric SMILES:CC(C)C[C@@H](C(=O)NC(=O)[C@H](CC(C)C)NC(=O)OCC1=CC=CC=C1)NC(CC2=CC=CC=C2)C=O

Technology Process of N-Benzyloxycarbonyl-leucyl-leucyl-phenylalaninal

There total 9 articles about N-Benzyloxycarbonyl-leucyl-leucyl-phenylalaninal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 186961-77-3
((S)-1-{(S)-1-[(R)-1-(Methoxy-methyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-3-methyl-butylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester

: 143839-79-6
{(S)-1-[(S)-1-((R)-1-Formyl-2-phenyl-ethylcarbamoyl)-3-methyl-butylcarbamoyl]-3-methyl-butyl}-carbamic acid benzyl ester

Guidance literature:: With lithium aluminium tetrahydride;
DOI:10.1016/S0960-894X(96)00559-8

Reference yield:

: 186961-76-2
((S)-1-{(S)-1-[(S)-1-(Methoxy-methyl-carbamoyl)-2-phenyl-ethylcarbamoyl]-3-methyl-butylcarbamoyl}-3-methyl-butyl)-carbamic acid benzyl ester

: 133429-58-0,143839-79-6
N-benzyloxycarbonyl-leucyl-leucyl-phenylalanal

Guidance literature:: With lithium aluminium tetrahydride;
DOI:10.1016/S0960-894X(96)00559-8

Reference yield:

: 13734-34-4
N-tert-butoxycarbonyl-L-phenylalanine

: 133429-58-0,143839-79-6
N-benzyloxycarbonyl-leucyl-leucyl-phenylalanal

Guidance literature:: Multi-step reaction with 4 steps

1: EDC, HOBt

2: TFA

3: EDC, HOBt

4: LAH

With lithium aluminium tetrahydride; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid;
DOI:10.1016/S0960-894X(96)00559-8