4-Hydroxy-4,4-diphenylbutanoic acid

Base Information

• Chemical Name: 4-Hydroxy-4,4-diphenylbutanoic acid
• CAS No.: 32858-92-7
• Molecular Formula: C16H16O3
• Molecular Weight: 256.2964
• NSC Number: 129394
• DSSTox Substance ID: DTXSID60299312
• Wikidata: Q82041623
• Mol file: 32858-92-7.mol

Synonyms:32858-92-7;4-hydroxy-4,4-diphenylbutanoic acid;NSC129394;DTXSID60299312;NSC-129394

Chemical Property of 4-Hydroxy-4,4-diphenylbutanoic acid

Chemical Property:

• Vapor Pressure: 7.53E-09mmHg at 25°C
• Boiling Point: 449.1°Cat760mmHg
• Flash Point: 239.5°C
• Density: 1.212g/cm³
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 256.109944368
• Heavy Atom Count: 19
• Complexity: 270

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(CCC(=O)O)(C2=CC=CC=C2)O

Technology Process of 4-Hydroxy-4,4-diphenylbutanoic acid

There total 6 articles about 4-Hydroxy-4,4-diphenylbutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-hydroxy-4,4-diphenyl-but-2-ynoic acid (29262-25-7) → γ,γ-diphenyl-γ-hydroxybutyric acid (32858-92-7)

Guidance literature:

With diethyl ether; platinum; Hydrogenation;

Reference yield:

5,5-diphenyldihydrofuran-2(3H)-one (7746-94-3) → γ,γ-diphenyl-γ-hydroxybutyric acid (32858-92-7)

Guidance literature:

With potassium carbonate;

Reference yield:

1,1-diphenyloxirane (882-59-7) → γ,γ-diphenyl-γ-hydroxybutyric acid (32858-92-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) Na, ethanol / 1) 2 h , heating 2) 3 h , reflux

2: 2 h / Heating

With ethanol; sodium;

upstream raw materials:

5,5-diphenyldihydrofuran-2(3H)-one

4-hydroxy-4,4-diphenyl-but-2-ynoic acid

3-Ethoxycarbonyl-4,5-dihydro-5,5-diphenyl-2(3H)-furanon

1,1-diphenyloxirane

Downstream raw materials:

4-hydroxy-4,4-diphenyl-butyric acid methyl ester

5,5-diphenyldihydrofuran-2(3H)-one