CHEMBRDG-BB 5118935

Base Information

• Chemical Name: CHEMBRDG-BB 5118935
• CAS No.: 29262-25-7
• Molecular Formula: C₁₆H₁₂O₃
• Molecular Weight: 252.269
• Mol file: 29262-25-7.mol

Synonyms:CHEMBRDG-BB 5118935;4-HYDROXY-4,4-DIPHENYLBUT-2-YNOIC ACID

Chemical Property of CHEMBRDG-BB 5118935

Chemical Property:

• PSA: 57.53000
• LogP: 2.01050

Purity/Quality:

4-HYDROXY-4,4-DIPHENYL-2-BUTYNOIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of CHEMBRDG-BB 5118935

There total 7 articles about CHEMBRDG-BB 5118935 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethynyldimagnesium dibromide (4301-15-9) + benzophenone (119-61-9) → 1,1,4,4-tetraphenyl-2-butyne-1,4-diol (1483-74-5) + 4-hydroxy-4,4-diphenyl-but-2-ynoic acid (29262-25-7)

Guidance literature:

With diethyl ether; at -10 ℃; anschliessendes Einleiten von Kohlendioxid;

Reference yield:

1,1-diphenyl-but-2-yne-1,4-diol (15807-08-6) → 4-hydroxy-4,4-diphenyl-but-2-ynoic acid (29262-25-7)

Guidance literature:

With chromium(VI) oxide;

Reference yield:

benzophenone (119-61-9) → 4-hydroxy-4,4-diphenyl-but-2-ynoic acid (29262-25-7)

Guidance literature:

Multi-step reaction with 2 steps

1: KOH; THF

2: CrO₃

With tetrahydrofuran; chromium(VI) oxide; potassium hydroxide;

upstream raw materials:

ethynyldimagnesium dibromide

benzophenone

1,1-diphenyl-but-2-yne-1,4-diol

ethylmagnesium bromide

Downstream raw materials:

γ,γ-diphenyl-γ-hydroxybutyric acid

4-hydroxy-4,4-diphenyl-but-2-ynoic acid amide