1,8-Dimethylquinolin-1-ium iodide

Base Information

• Chemical Name: 1,8-Dimethylquinolin-1-ium iodide
• CAS No.: 32596-80-8
• Molecular Formula: C₁₁H₁₂N*I
• Molecular Weight: 285.127
• DSSTox Substance ID: DTXSID10500344
• NSC Number: 117174
• Mol file: 32596-80-8.mol

Synonyms:32596-80-8;1,8-Dimethylquinolin-1-ium iodide;SCHEMBL8553864;DTXSID10500344;NSC117174;NSC-117174

Chemical Property of 1,8-Dimethylquinolin-1-ium iodide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: g/cm³
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 285.00145
• Heavy Atom Count: 13
• Complexity: 155

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=C2C(=CC=C1)C=CC=[N+]2C.[I-]

Technology Process of 1,8-Dimethylquinolin-1-ium iodide

There total 4 articles about 1,8-Dimethylquinolin-1-ium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

8-methylquinoline (611-32-5) + methyl iodide (74-88-4) → 1,8-dimethylquinolin-1-ium iodide (32596-80-8)

Guidance literature:

In acetonitrile; at 80 ℃; for 16h;

DOI:10.1021/acs.joc.0c02321

Reference yield:

8-methylquinoline (611-32-5) + 6-iodo-1,8-dimethyl-1,2,3,4-tetrahydroquinolin-2-one + methyl iodide (74-88-4) → 1,8-dimethylquinolin-1-ium iodide (32596-80-8)

Guidance literature:

In diethyl ether; acetonitrile;

Reference yield:

o-toluidine (95-53-4) → 1,8-dimethylquinolin-1-ium iodide (32596-80-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid; o-nitro-toluene

2: im Rohr

With 1-methyl-2-nitrobenzene; sulfuric acid;

upstream raw materials:

8-methylquinoline

nitrobenzene

methyl iodide

o-toluidine