1,9-Pyrazoloanthrone

Base Information

Chemical Name:1,9-Pyrazoloanthrone
CAS No.:129-56-6
Molecular Formula:C14H8N2O
Molecular Weight:220.23
Hs Code.:29339900
European Community (EC) Number:204-955-6
NSC Number:75890
UNII:1TW30Y2766
DSSTox Substance ID:DTXSID2040525
Nikkaji Number:J55.382D
Wikipedia:1,9-Pyrazoloanthrone
Wikidata:Q4545713,Q110177831
Pharos Ligand ID:TQASGT2ZFMFV
Metabolomics Workbench ID:146412
ChEMBL ID:CHEMBL7064,CHEMBL1725279
Mol file:129-56-6.mol

Synonyms:1,9-pyrazoloanthrone;2h-dibenzo(cd,g)indazol-6-one;anthra(1,9-cd)pyrazol-6(2H)-one;NSC-75890;NSC75890;pyrazolanthrone;SP600125

Suppliers and Price of 1,9-Pyrazoloanthrone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
SP 600125
10mg
$ 366.00

TRC
SP600125
50mg
$ 75.00

Tocris
SP600125 ≥98%(HPLC)
50
$ 406.00

Tocris
SP600125 ≥98%(HPLC)
10
$ 98.00

TCI Chemical
Anthra[1,9-cd]pyrazol-6(2H)-one >98.0%(HPLC)
25mg
$ 62.00

Sigma-Aldrich
JNK Inhibitor II
5mg
$ 74.92

Sigma-Aldrich
SP600125 ≥98% (HPLC)
10 mg
$ 106.00

Sigma-Aldrich
JNK Inhibitor II
50mg
$ 387.00

Sigma-Aldrich
JNK Inhibitor II
25mg
$ 246.00

Sigma-Aldrich
SP600125 ≥98% (HPLC)
50 mg
$ 456.00

Total 80 raw suppliers

Chemical Property of 1,9-Pyrazoloanthrone

Chemical Property:

Appearance/Colour:yellow
Vapor Pressure:1.01E-09mmHg at 25°C
Melting Point:281~282 °C
Refractive Index:1.799
Boiling Point:489.28 °C at 760 mmHg
PKA:11.75±0.20(Predicted)
Flash Point:246.787 °C
PSA：45.75000
Density:1.463 g/cm³
LogP:2.66730
Storage Temp.:2-8°C
Solubility.:H2O: insoluble
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:220.063662883
Heavy Atom Count:17
Complexity:343

Purity/Quality:

99%, ^*data from raw suppliers

SP 600125 ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C3=NNC4=CC=CC(=C43)C2=O
General Description 1,9-Pyrazoloanthrone, also known as SP 600125 or anthra[1,9-cd]pyrazol-6(2H)-one, is a compound with diverse applications, including its role as a c-Jun N-terminal kinase (JNK) inhibitor and a fluoride ion probe. While SP600125 is a widely used JNK inhibitor, its lack of specificity has prompted the development of halogenated derivatives to improve selectivity. Additionally, 1,9-pyrazoloanthrone derivatives exhibit colorimetric and fluorometric properties, making them useful as selective fluoride ion probes, where they display a distinct color change and fluorescence response upon fluoride binding.

Technology Process of 1,9-Pyrazoloanthrone

There total 5 articles about 1,9-Pyrazoloanthrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 82-45-1
1-amino-9,10-anthracenedione

: 129-56-6
2H-dibenzo[cd,g]indazol-6-one

Guidance literature:: 1-amino-9,10-anthracenedione; With sulfuric acid; sodium nitrite; In water; at 45 ℃; for 8h;

With sodium metabisulfite; sodium hydroxide; In water; at 10 - 90 ℃; for 17h; pH=12.5 - 12.8; Temperature; pH-value; Time;