2-[(2-Methoxyphenyl)methyl]naphthalene

Base Information

Chemical Name:2-[(2-Methoxyphenyl)methyl]naphthalene
CAS No.:68299-62-7
Molecular Formula:C18H16O
Molecular Weight:248.324
Hs Code.:
DSSTox Substance ID:DTXSID90497364
Wikidata:Q82346827

Synonyms:2-[(2-Methoxyphenyl)methyl]naphthalene;68299-62-7;SCHEMBL25798810;DTXSID90497364

Suppliers and Price of 2-[(2-Methoxyphenyl)methyl]naphthalene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 2-[(2-Methoxyphenyl)methyl]naphthalene

Chemical Property:

XLogP3:5.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:248.120115130
Heavy Atom Count:19
Complexity:275

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1CC2=CC3=CC=CC=C3C=C2

Technology Process of 2-[(2-Methoxyphenyl)methyl]naphthalene

There total 6 articles about 2-[(2-Methoxyphenyl)methyl]naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: (2-methoxyphenyl)(naphthalen-2-yl)methanol

: 68299-62-7
2-(2-methoxybenzyl)naphthalene

Guidance literature:: With triethylsilane; sodium hydrogencarbonate; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;
DOI:10.1016/j.bmc.2013.10.051

Reference yield: 61.0%

: 100-66-3
methoxybenzene

: diethyl (naphthalen-2-ylmethyl) phosphate

: 32891-91-1
2-(4-methoxy-benzyl)-naphthalene

: 68299-62-7
2-(2-methoxybenzyl)naphthalene

Guidance literature:: With aluminium(III) triflate; In neat (no solvent); at 100 ℃; for 0.5h; regioselective reaction;
DOI:10.1002/ejoc.202000077

Reference yield:

: 66-99-9
β-naphthaldehyde

: 68299-62-7
2-(2-methoxybenzyl)naphthalene

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium; iodine / tetrahydrofuran / 6.17 h / Sealed tube; Inert atmosphere; Reflux

1.2: 20 °C / Sealed tube; Inert atmosphere

2.1: trifluoroacetic acid; triethylsilane; sodium hydrogencarbonate / dichloromethane / 1 h / 20 °C / Inert atmosphere

With triethylsilane; iodine; sodium hydrogencarbonate; magnesium; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.bmc.2013.10.051