1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide

Base Information

Chemical Name:1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide
CAS No.:83575-44-4
Molecular Formula:C25H30 N6 O7
Molecular Weight:526.549
Hs Code.:
Mol file:83575-44-4.mol

Synonyms:1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide

Suppliers and Price of 1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide

Chemical Property:

Vapor Pressure:5.56E-29mmHg at 25°C
Boiling Point:847.4°C at 760 mmHg
Flash Point:466.3°C
PSA：193.16000
Density:1.373g/cm³
LogP:4.54690

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide

There total 2 articles about 1-(benzyloxycarbonyl)-L-prolyl-N5-carbamoyl-N-(4-nitrophenyl)-L-ornithinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 83575-38-6
N₁-carbamoyl-3-benzyloxycarbonylamidopiperidin-2-one

: 3304-59-4
N-benzyloxycarbonyl-L-proline p-nitrophenyl ester

: 83575-44-4
benzyloxycarbonyl-L-prolyl-L-citrulline p-nitroanilide

Guidance literature:: With triethylamine; In N,N-dimethyl-formamide; for 18h; Ambient temperature;
DOI:10.1016/0040-4020(82)80232-9

Reference yield:

: 6692-89-3,13594-52-0
N^α-benzyloxy-carbonyl-L-citrulline

: 83575-44-4
benzyloxycarbonyl-L-prolyl-L-citrulline p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: 30 percent / PCl₃, pyridine / 1.) -20 deg C, 30 min., 2.) room temp., 30 min., 3.) room temp., 3 days

2: 79 percent / triethylamine / dimethylformamide / 18 h / Ambient temperature

With pyridine; triethylamine; phosphorus trichloride; In N,N-dimethyl-formamide;
DOI:10.1016/0040-4020(82)80232-9

Reference yield:

: 83575-44-4
benzyloxycarbonyl-L-prolyl-L-citrulline p-nitroanilide

: 83575-46-6
benzyloxycarbonylglycyl-L-prolyl-L-citrulline p-nitroanilide

Guidance literature:: Multi-step reaction with 2 steps

1: HBr in HOAc / acetic acid / 1.5 h / Ambient temperature

2: 60 percent / triethylamine / dimethylformamide / 48 h / Ambient temperature

With hydrogen bromide; triethylamine; In acetic acid; N,N-dimethyl-formamide;
DOI:10.1016/0040-4020(82)80232-9