(5beta)-17-hydroxypregnane-3,11,20-trione

Base Information

• Chemical Name: (5beta)-17-hydroxypregnane-3,11,20-trione
• CAS No.: 10455-93-3
• Molecular Formula: C21H30 O4
• Molecular Weight: 346.467
• Mol file: 10455-93-3.mol

Synonyms:NSC15470

Chemical Property of (5beta)-17-hydroxypregnane-3,11,20-trione

Chemical Property:

• Vapor Pressure: 3.43E-12mmHg at 25°C
• Boiling Point: 502.2°Cat760mmHg
• Flash Point: 271.6°C
• Density: 1.179g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (5beta)-17-hydroxypregnane-3,11,20-trione

There total 14 articles about (5beta)-17-hydroxypregnane-3,11,20-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3α,17-dihydroxy-5β-pregnane-11,20-dione (641-78-1) → 17-hydroxy-5β-pregnane-3,11,20-trione (10455-93-3)

Guidance literature:

With chromium(VI) oxide; acetic acid;

DOI:10.1021/ja01184a047

Reference yield:

16β-bromo-17-hydroxy-5β-pregnane-3,11,20-trione (111584-19-1) → 17-hydroxy-5β-pregnane-3,11,20-trione (10455-93-3)

Guidance literature:

With Lindlar's catalyst; ethanol; Hydrogenation;

DOI:10.1021/ja01553a063

Reference yield:

→ 17-hydroxy-5β-pregnane-3,11,20-trione (10455-93-3)

Guidance literature:

With pyridine; osmium(VIII) oxide; benzene; anschliessend mit wss.Na₂SO₃;

DOI:10.1021/ja01184a047

upstream raw materials:

16β-bromo-17-hydroxy-5β-pregnane-3,11,20-trione

3α,17-dihydroxy-5β-pregnane-11,20-dione

pyridine

benzene

Downstream raw materials:

17-hydroxy-pregn-4-ene-3,11,20-trione

3α,17-dihydroxy-5β-pregnane-11,20-dione

11β,17-dihydroxy-5β-pregnane-3,20-dione

21-acetoxy-17-hydroxy-5β-pregnane-3,11,20-trione