1-[4,4-Bis(4-fluorophenyl)butyl]piperazine

Base Information

Chemical Name:1-[4,4-Bis(4-fluorophenyl)butyl]piperazine
CAS No.:5631-35-6
Molecular Formula:C20H24 F2 N2
Molecular Weight:330.421
Hs Code.:
European Community (EC) Number:227-070-7
DSSTox Substance ID:DTXSID90204853
Nikkaji Number:J225.066G
Wikidata:Q83078324
ChEMBL ID:CHEMBL81206
Mol file:5631-35-6.mol

Synonyms:1-[4,4-bis(4-fluorophenyl)butyl]piperazine;5631-35-6;EINECS 227-070-7;1-(4,4-Bis(4-fluorophenyl)butyl)piperazine;CHEMBL81206;SCHEMBL2268114;DTXSID90204853;AKOS024288394;C20-H24-F2-N2;1-[4,4-bis(p-fluorophenyl)butyl]piperazine;1-[4,4-Di(4-fluorophenyl)butyl]piperazine;1-[4,4-bis(p-fluorophenyl)butyl]-piperazine;Piperazine, 1-(4,4-bis(4-fluorophenyl)butyl)-

Suppliers and Price of 1-[4,4-Bis(4-fluorophenyl)butyl]piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-[4,4-BIS-(4-FLUOROPHENYL)BUTYL]PIPERAZINE 95.00%
5MG
$ 503.90

Total 6 raw suppliers

Chemical Property of 1-[4,4-Bis(4-fluorophenyl)butyl]piperazine

Chemical Property:

Vapor Pressure:3.08E-08mmHg at 25°C
Boiling Point:448.5°Cat760mmHg
Flash Point:225.1°C
PSA：15.27000
Density:1.112g/cm³
LogP:4.04880
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:6
Exact Mass:330.19075510
Heavy Atom Count:24
Complexity:322

Purity/Quality:

99% ^*data from raw suppliers

1-[4,4-BIS-(4-FLUOROPHENYL)BUTYL]PIPERAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(CCN1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F

Technology Process of 1-[4,4-Bis(4-fluorophenyl)butyl]piperazine

There total 3 articles about 1-[4,4-Bis(4-fluorophenyl)butyl]piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87349-62-0
4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-carboxylic acid ethyl ester

: 5631-35-6
1-[4,4-bis(4-fluorophenyl)butyl]piperazine

Guidance literature:: With potassium hydroxide; In ethanol; at 120 ℃; for 2.5h; Yield given;
DOI:10.1135/cccc19803182

Reference yield:

: 57668-61-8
4,4'-(4-bromobutane-1,1-diyl)bis(fluorobenzene)

: 5631-35-6
1-[4,4-bis(4-fluorophenyl)butyl]piperazine

Guidance literature:: Multi-step reaction with 2 steps

1: 6 h / 120 °C

2: KOH / ethanol / 2.5 h / 120 °C

With potassium hydroxide; In ethanol;
DOI:10.1135/cccc19803182