Ala-Ser

Base Information

• Chemical Name: Ala-Ser
• CAS No.: 3303-41-1
• Molecular Formula: C6H12N2O4
• Molecular Weight: 176.172
• Hs Code.: 2924199090
• Nikkaji Number: J80.687K
• Wikidata: Q27140486
• Metabolomics Workbench ID: 78671
• ChEMBL ID: CHEMBL190179
• Mol file: 3303-41-1.mol

Synonyms:H-Ala-Ser-OH;Ala-Ser;3303-41-1;L-alanyl-L-serine;CHEMBL190179;CHEBI:73394;(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-hydroxypropanoic acid;(S)-2-((S)-2-aminopropanamido)-3-hydroxypropanoic acid;Alanyl-Serine;(2S)-2-[(2S)-2-aminopropanamido]-3-hydroxypropanoic acid;Ala-Ser-OH;Alanylserin;N-alanylserine;AS dipeptide;A-S Dipeptide;L-Ala-L-Ser;Alanine Serine dipeptide;Alanine-Serine dipeptide;L-Serine, N-L-alanyl-;SCHEMBL7123863;HY-P4244;BDBM50169132;MFCD00066028;AKOS010408397;CS-0653323;F74290;J-018982;Q27140486;(S)-2-((S)-2-Amino-propionylamino)-3-hydroxy-propionic acid;A-S

Chemical Property of Ala-Ser

Chemical Property:

• Boiling Point: 486.7°Cat760mmHg
• Flash Point: 248.2°C
• PSA: 112.65000
• Density: 1.354g/cm³
• LogP: -1.01350
• Storage Temp.: −20°C
• XLogP3: -4.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 176.07970687
• Heavy Atom Count: 12
• Complexity: 182

Purity/Quality:

99%+, ^*data from raw suppliers

H-Ala-Ser-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)NC(CO)C(=O)O)N
• Isomeric SMILES: C[C@@H](C(=O)N[C@@H](CO)C(=O)O)N

Technology Process of Ala-Ser

There total 1 articles about Ala-Ser which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

AcMet-Ala-Ser → N-acetyl-l-methionine (65-82-7) + N-L-alanyl-L-serine (3303-41-1)

Guidance literature:

With perchloric acid; 3-(trimethylsilyl)-1-propanesulfonic acid,sodium salt; dinuclear palladium(II) hexaazacyclooctadecane; In water-d2; at 50 ℃; pH=1.0; Further Variations:; molar ratios; Kinetics;

DOI:10.1039/b500210a

Reference yield:

N-L-alanyl-L-serine (3303-41-1) → L-alanin (56-41-7,25191-17-7,18875-37-1) + L-serin (56-45-1,83245-15-2)

Guidance literature:

With zinc(II) chloride; In various solvent(s); at 50 ℃; pH=7.0; Further Variations:; Reagents; Kinetics;

DOI:10.1039/b209565c

Reference yield:

N-L-alanyl-L-serine (3303-41-1) + [(R)-1-[(S)-1-(Hydrazinocarbonylmethyl-carbamoyl)-ethylcarbamoyl]-2-(4-methoxy-benzylsulfanyl)-ethyl]-carbamic acid tert-butyl ester (86895-16-1) → Boc-Cys(MBzl)-Ala-Gly-Ala-Ser-OH (86895-22-9)

Guidance literature:

With hydrogenchloride; tert.-butylnitrite; triethylamine; Yield given. Multistep reaction; 1.) DMF, dioxane, -25 degC, 10 min, 2.) H₂O, cold;

Downstream raw materials:

Boc-Cys(MBzl)-Ala-Gly-Ala-Ser-OH

L-alanin

L-serin

Refernces