(E)-5-phenylpent-4-en-1-ol

Base Information

• Chemical Name: (E)-5-phenylpent-4-en-1-ol
• CAS No.: 13159-16-5
• Molecular Formula: C11H14 O
• Molecular Weight: 162.232
• Hs Code.: 2906299090
• Nikkaji Number: J473.431I,J2.577.088I
• Mol file: 13159-16-5.mol

Synonyms:5-phenyl-4-pentenyl-1-alcohol;5-phenylpent-4-enyl-1-ol

Chemical Property of (E)-5-phenylpent-4-en-1-ol

Chemical Property:

• Vapor Pressure: 0.00193mmHg at 25°C
• Boiling Point: 279.3°Cat760mmHg
• Flash Point: 122.5°C
• PSA: 20.23000
• Density: 1.008g/cm³
• LogP: 2.47230
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 162.104465066
• Heavy Atom Count: 12
• Complexity: 123

Purity/Quality:

97% ^*data from raw suppliers

4-Penten-1-ol,5-phenyl-,(4E)- 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CCCCO
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/CCCO
• Description: PPA is the product of peroxidase-catalyzed reduction of PPHP. It can be used as a reference standard for HPLC analysis of peroxidase assays.

Technology Process of (E)-5-phenylpent-4-en-1-ol

There total 139 articles about (E)-5-phenylpent-4-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(4E)-5-phenyl-4-pentenoic acid (28525-69-1) → (E)-5-phenyl-4-penten-1-ol (13159-16-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Inert atmosphere;

DOI:10.1021/ol200840e

Reference yield: 100.0%

(E)-ethyl 5-phenylpent-4-enoate (22768-07-6,121746-04-1,93845-04-6) → (E)-5-phenyl-4-penten-1-ol (13159-16-5)

Guidance literature:

With diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane; at -78 ℃; for 4h;

DOI:10.1021/jo0483466

Reference yield: 99.0%

5-phenylpent-4-yn-1-ol (24595-58-2) → (E)-5-phenyl-4-penten-1-ol (13159-16-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 20h; Heating;

DOI:10.1021/ja029139v

upstream raw materials:

5-phenylpent-4-yn-1-ol

3,4-dihydro-2H-pyran

benzaldehyde

(4-hydroxybutyl)-triphenylphosphonium bromide

Downstream raw materials:

(E)-5-phenylpent-4-en-1-yl 4-methylbenzenesulfonate

2-((E)-5-phenylpent-4-enyloxy)tetrahydro-2H-pyran

(E)-(5-iodopent-1-en-1-yl)benzene

trans-2-methyl-7-phenyl-1,6-heptadien-3-ol

Refernces

• 1、 Cowan,Baum. "". . p. 1153,1155, 1160. Retrieved 1971.
• 2、 Bond?i?, Aleksandra M.,Bond?i?, Bojan P.,D?ambaski, Zdravko,Kokotos, Christoforos G.,Triandafillidi, Ierasia. "Organocatalytic, Organic Oxidant Promoted, Enamine C?H Oxidation/Cyclopropanation Reaction". . p. 4002 - 4008. Retrieved 2021.
• 3、 Chen, Dake,Berhane, Ilyas A.,Chemler, Sherry R.. "Copper-Catalyzed Enantioselective Hydroalkoxylation of Alkenols for the Synthesis of Cyclic Ethers". supporting information. p. 7409 - 7414. Retrieved 2020/06/29.