4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl-

Base Information

Chemical Name:4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl-
CAS No.:687639-17-4
Molecular Formula:C₂₀H₁₂Cl₂N₂O
Molecular Weight:367.234
Hs Code.:
DSSTox Substance ID:DTXSID20439090
Wikidata:Q82254977
ChEMBL ID:CHEMBL2238065

Synonyms:687639-17-4;4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl-;6-chloro-3-(4-chlorophenyl)-2-phenylquinazolin-4(3h)-one;SCHEMBL5758700;6-chloro-3-(4-chlorophenyl)-2-phenyl-quinazolin-4-one;CHEMBL2238065;DTXSID20439090;6-chloro-3-(4-chlorophenyl)-2-phenyl-3,4-dihydroquinazolin-4-one

Suppliers and Price of 4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl-

Chemical Property:

XLogP3:5.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:366.0326684
Heavy Atom Count:25
Complexity:524

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC3=C(C=C(C=C3)Cl)C(=O)N2C4=CC=C(C=C4)Cl

Technology Process of 4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl-

There total 3 articles about 4(3H)-Quinazolinone, 6-chloro-3-(4-chlorophenyl)-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 19407-45-5
2-benzamido-5-chlorobenzoic acid

: 106-47-8
4-chloro-aniline

: 687639-17-4
6-chloro-3-(4-chlorophenyl)-2-phenylquinazolin-4(3H)-one

Guidance literature:: With dicyclohexyl-carbodiimide; for 0.133333h; Microwave irradiation;
DOI:10.1007/s00044-011-9826-7

Reference yield:

: 98-88-4
benzoyl chloride

: 687639-17-4
6-chloro-3-(4-chlorophenyl)-2-phenylquinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / 1 h

2: dicyclohexyl-carbodiimide / 0.13 h / Microwave irradiation

With dicyclohexyl-carbodiimide; sodium hydroxide;
DOI:10.1007/s00044-011-9826-7

Reference yield:

: 635-21-2
5-chloroanthranilic acid

: 687639-17-4
6-chloro-3-(4-chlorophenyl)-2-phenylquinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / 0 - 20 °C

2: acetic acid / 6 h / Reflux

With pyridine; acetic acid;
DOI:10.14233/ajchem.2018.21547