Technology Process of Diphenylisopropoxyborane
There total 8 articles about Diphenylisopropoxyborane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride; tert.-butyl lithium;
In
diethyl ether;
under N2; to cold (-98 °C) soln. of boron compd. in Et2O slowly added MeLi, stirred for 0.5 h, warmed to room temp., stirred for 0.5 h,Li(BMe4) detected by (11)B NMR, cooled to 0 °C, added soln. of HCl in Et2O, stirred for 15 min, warmed; not isolated, monitored by (11)B NMR;
DOI:10.1021/om50004a009
- Guidance literature:
-
In
diethyl ether;
byproducts: LiCl, 2-propanol; 1 equiv of PhLi slowly adding to a soln. of the boronic ester at -78°C, stirring for 3 h at the same temp., 1 equiv of anhydrous HCl in ether adding, warming to room temp., stirring for 15 min; product content detd. by (11)B NMR spectrum;
DOI:10.1021/om00129a019
- Guidance literature:
-
In
diethyl ether;
byproducts: LiCl, 2-propanol; 1 equiv of PhLi slowly adding to a soln. of the boronic ester at -78°C, stirring for 3 h at the same temp., 1 equiv of anhydrous HCl in ether adding, warming to room temp., decanting from the ppt. of LiCl, washing with ether, evavpg.; isolated by fractional distillation, identified by elem. anal., NMR, UVand mass spectra;
DOI:10.1021/om00129a019
