1-(N-Carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid

Base Information

Chemical Name:1-(N-Carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid
CAS No.:97975-31-0
Molecular Formula:C22H22 N2 O7
Molecular Weight:0
Hs Code.:
Mol file:97975-31-0.mol

Synonyms:1-(N-carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid;1-CDGIC

Suppliers and Price of 1-(N-Carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(N-Carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid

Chemical Property:

Vapor Pressure:3.77E-26mmHg at 25°C
Boiling Point:787.8°Cat760mmHg
Flash Point:430.2°C
PSA：136.73000
Density:1.404g/cm³
LogP:2.45810
XLogP3:2.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:9
Exact Mass:426.14270105
Heavy Atom Count:31
Complexity:677

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(N(C2=CC=CC=C21)C(=O)CCC(C(=O)O)NC(=O)OCC3=CC=CC=C3)C(=O)O
Isomeric SMILES:C1[C@H](N(C2=CC=CC=C21)C(=O)CC[C@H](C(=O)O)NC(=O)OCC3=CC=CC=C3)C(=O)O

Technology Process of 1-(N-Carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid

There total 1 articles about 1-(N-Carbobenzoxy-gamma-glutamyl)indoline-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 71869-80-2
benzyl (R)-(2,6-dioxotetrahydro-2H-pyran-3-yl)carbamate

: 82923-76-0
(S)-5-methoxyindol-2,3-dihydro-2-carboxylic acid hydrochloride

: 97975-31-0
1-(N-carbobenzoxy-γ-D-glutamyl)indoline-2(S)-carboxylic acid

Guidance literature:: With pyridine; at 80 ℃; for 5h;
DOI:10.1021/jm00149a011

Reference yield: 70.0%

: 64-17-5
ethanol

: 97975-31-0
1-(N-carbobenzoxy-γ-D-glutamyl)indoline-2(S)-carboxylic acid

: 97975-53-6
ethyl 1-<4-(N-carbobenzoxyamino)-4-carboethoxy-4(R)-butyryl>indoline-2(S)-carboxylic acid

Guidance literature:: With sulfuric acid; for 3h; Heating;
DOI:10.1021/jm00149a011

Reference yield:

: 97975-31-0
1-(N-carbobenzoxy-γ-D-glutamyl)indoline-2(S)-carboxylic acid

: 97975-36-5
1-[N-(phenylcarbamoyl)-γ-D-glutamyl]indoline-2(S)-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 74 percent / H₂ / 10percent Pd/C / ethanol / 16 h / 760 Torr

2: 67 percent / dimethylformamide / 48 h / Ambient temperature

With hydrogen; palladium on activated charcoal; In ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00149a011