3-(2-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

Base Information

• Chemical Name: 3-(2-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER
• CAS No.: 70311-27-2
• Molecular Formula: C12H16O3
• Molecular Weight: 208.257
• Mol file: 70311-27-2.mol

Synonyms:ethyl 2-(2-methoxyphenyl)propionate;ethyl 3-(2-methoxyphenyl)propionate;3-(2-Methoxyphenyl)propionic acid ethyl ester;3-(2-methoxyphenyl)propanoic acid ethyl ester;ethyl 3-(o-methoxyphenyl)-propanoate;2-methoxybenzenepropanoic acid ethyl ester;

Chemical Property of 3-(2-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

Chemical Property:

• Vapor Pressure: 0.00373mmHg at 25°C
• Boiling Point: 280.7oC at 760 mmHg
• Flash Point: 112.8oC
• PSA: 35.53000
• Density: 1.045g/cm3
• LogP: 2.19090

Purity/Quality:

95% ^*data from raw suppliers

3-(2-Methoxyphenyl)propionicacidethylester ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(2-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER

There total 17 articles about 3-(2-METHOXY-PHENYL)-PROPIONIC ACID ETHYL ESTER which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-methoxy-benzenepropanoic acid (6342-77-4) + Diethyl carbonate (105-58-8,76619-83-5) → 2-methoxybenzenepropanoic acid ethyl ester (70311-27-2)

Guidance literature:

With Novozym 435; acylase I from Aspergillus melleus; amano lipase AK from pseudomonas fluorescens; lipase from wheat germ; papaine; In toluene; at 40 ℃; for 48h; Mechanism; Enzymatic reaction;

DOI:10.1016/j.molcatb.2014.02.020

Reference yield: 80.0%

acrylaldehyde diethyl acetal (3054-95-3) + 4-iodoanisol (529-28-2) → 2-methoxybenzenepropanoic acid ethyl ester (70311-27-2)

Guidance literature:

With tributyl-amine; tetrabutyl-ammonium chloride; palladium diacetate; In N,N-dimethyl-formamide; at 90 ℃; for 7.5h;

DOI:10.1055/s-2003-39900

Reference yield:

2-bromoanisole (578-57-4) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3-(2-methoxyphenyl)prop-2-enoate (24393-54-2) + 2-methoxybenzenepropanoic acid ethyl ester (70311-27-2)

Guidance literature:

With pyridine; [2,2]bipyridinyl; triethylamine; cobalt(II) bromide; In acetonitrile; at 70 ℃; Electrochemical reaction;

DOI:10.1016/S0040-4039(02)01286-8

upstream raw materials:

2-methoxy-benzenepropanoic acid

ethyl 3-(2-methoxyphenyl)prop-2-enoate

3-(2-methoxy-phenyl)-3-oxo-propionic acid ethyl ester

ethyl 3-(2-methoxyphenyl)acrylate

Downstream raw materials:

3-(2-methoxyphenyl)propan-1-ol

3-(3-Ethoxy-3-oxopropyl)-4-methoxy-δ-oxobenzenepentanoic Acid

2-methoxy-benzenepropanoic acid

5-(2'-methoxyxyphenyl)pentanoic acid