Ethyl 2-methoxycinnamate

Base Information

Chemical Name:Ethyl 2-methoxycinnamate
CAS No.:33877-05-3
Molecular Formula:C12H14 O3
Molecular Weight:206.241
Hs Code.:
DSSTox Substance ID:DTXSID901282787
Mol file:33877-05-3.mol

Synonyms:ethyl 2-methoxycinnamate;DTXSID901282787;AKOS017265412;Ethyl 3-(2-methoxyphenyl)-2-propenoate

Suppliers and Price of Ethyl 2-methoxycinnamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Ethyl3-(2-methoxyphenyl)acrylate 97%
10g
$ 330.00

Crysdot
Ethyl3-(2-methoxyphenyl)acrylate 97%
25g
$ 594.00

American Custom Chemicals Corporation
ETHYL-O-METHOXYCINNAMATE 95.00%
5MG
$ 497.89

Advanced Chemicals Intermediatesced Chemicals Intermediates
(E)-3-(2-Methoxy-phenyl)-acrylicacidethylester 95%+
1g
$ 94.25

Advanced Chemicals Intermediatesced Chemicals Intermediates
(E)-3-(2-Methoxy-phenyl)-acrylicacidethylester 95%+
5g
$ 268.25

Acints
(E)-3-(2-Methoxy-phenyl)-acrylicacidethylester 95%+
5g
$ 268.25

Acints
(E)-3-(2-Methoxy-phenyl)-acrylicacidethylester 95%+
1g
$ 94.25

Total 6 raw suppliers

Chemical Property of Ethyl 2-methoxycinnamate

Chemical Property:

Boiling Point:311.4°Cat760mmHg
Flash Point:127.3°C
PSA：35.53000
Density:1.08g/cm³
LogP:2.27150
XLogP3:2.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:206.094294304
Heavy Atom Count:15
Complexity:223

Purity/Quality:

99% ^*data from raw suppliers

Ethyl3-(2-methoxyphenyl)acrylate 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C=CC1=CC=CC=C1OC

Technology Process of Ethyl 2-methoxycinnamate

There total 13 articles about Ethyl 2-methoxycinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 529-28-2
4-iodoanisol

: 140-88-5,9003-32-1
ethyl acrylate

: 33877-05-3
ethyl 3-(2-methoxyphenyl)acrylate

Guidance literature:: With potassium carbonate; In dimethyl sulfoxide; at 120 ℃; for 3h; Schlenk technique; Green chemistry;
DOI:10.1039/c7nj04361a

Reference yield: 89.0%

: 623-73-4
diazoacetic acid ethyl ester

: C₁₄H₁₃N₃O₅S

: 33877-05-3
ethyl 3-(2-methoxyphenyl)acrylate

Guidance literature:: C₁₄H₁₃N₃O₅S; With sodium hydride; In dichloromethane; at 20 ℃; for 1h; Glovebox;

diazoacetic acid ethyl ester; With silver trifluoroacetate; In dichloromethane; at 40 ℃; for 20h; Sealed tube;
DOI:10.1002/ejoc.201601610

Reference yield:

: 100-66-3
methoxybenzene

: 140-88-5,9003-32-1
ethyl acrylate

: 24393-56-4
ethyl (E)-3-(4-methoxyphenyl)prop-2-enoate

: 33877-04-2
3-methoxycinnamic acid ethyl ester

: 33877-05-3
ethyl 3-(2-methoxyphenyl)acrylate

Guidance literature:: With oxygen; palladium diacetate; ethyl 4,5-diphenylpyrazolo[1,5-a][1,8]naphthyridine-3-carboxylate; acetic acid; at 100 ℃; for 24h; under 760.051 Torr; Overall yield = 52 percent; Overall yield = 21 mg; regioselective reaction;
DOI:10.1021/acs.orglett.1c01040