1-(3'-C-methyl-beta-D-ribofuranosyl)uracil 5'-triphosphate

Base Information

Chemical Name:1-(3'-C-methyl-beta-D-ribofuranosyl)uracil 5'-triphosphate
CAS No.:87215-07-4
Molecular Formula:C₁₀H₁₇N₂O₁₅P₃
Molecular Weight:498.171
Hs Code.:
Mol file:87215-07-4.mol

Synonyms:1-(3’-C-methyl-beta-D-ribofuranosyl)uracil 5’-triphosphate

Suppliers and Price of 1-(3'-C-methyl-beta-D-ribofuranosyl)uracil 5'-triphosphate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 1-(3'-C-methyl-beta-D-ribofuranosyl)uracil 5'-triphosphate

Chemical Property:

PSA：293.80000
LogP:-2.11080

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-(3'-C-methyl-beta-D-ribofuranosyl)uracil 5'-triphosphate

There total 14 articles about 1-(3'-C-methyl-beta-D-ribofuranosyl)uracil 5'-triphosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 89157-89-1
diammonium salt of 1-(3-C-methyl-β-D-ribofuranosyl)uracil 5'-phosphate

: 87215-07-4
1-(3-C-methyl-β-D-ribofuranosyl)uracil 5'-triphosphate

Guidance literature:: With tributyl-amine; tri(n-butyl)ammonium pyrophosphate; 1,1'-carbonyldiimidazole; In water; N,N-dimethyl-formamide; at 20 ℃; for 16h;
DOI:10.1016/0008-6215(83)88357-8

Reference yield:

: 87215-06-3
1-(3-C-methyl-β-D-ribofuranosyl)uracil 5'-phosphate

: 87215-07-4
1-(3-C-methyl-β-D-ribofuranosyl)uracil 5'-triphosphate

Guidance literature:: 1-(3-C-methyl-β-D-ribofuranosyl)uracil 5'-phosphate; With tributyl-amine; 1,1'-carbonyldiimidazole; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

With bis(tri-n-butylammonium) pyrophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 24h; Further stages.;
DOI:10.1016/j.bmc.2008.05.013

Reference yield:

: 16831-81-5
((3aR,5R,6R,6aR)-6-hydroxy-2,2,6-trimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate

: 87215-07-4
1-(3-C-methyl-β-D-ribofuranosyl)uracil 5'-triphosphate

Guidance literature:: Multi-step reaction with 7 steps

1: 1.4 g / 4-(dimethylamino)pyridine / pyridine / 16 h / 20 °C

2: conc. H₂SO₄ / acetic acid / 96 h / 20 °C

3: 80 percent / hexamethyldisilazane, chlorotrimethylsilane, tin tetrachloride / acetonitrile / 16 h / 20 °C

4: 61 percent / NEt₃ / methanol / 20 h / 20 °C

6: 32 percent / 2-cyanoethyl pyridinium phosphate, 2,4,6-triisopropylbenzenesulfonyl chloride / 3 h / 20 °C

7: 40 percent / tributylamine, 1,1'-carbonyldiimidazole, tributylammonium pyrophosphate / H₂O; dimethylformamide / 16 h / 20 °C

With dmap; chloro-trimethyl-silane; 2,4,6-triisopropylphenylsulfonyl chloride; tributyl-amine; 2-cyanoethyl pyridinium phosphate; sulfuric acid; tin(IV) chloride; tri(n-butyl)ammonium pyrophosphate; triethylamine; 1,1,1,3,3,3-hexamethyl-disilazane; 1,1'-carbonyldiimidazole; In pyridine; methanol; water; acetic acid; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1016/0008-6215(83)88357-8