4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaMide

Base Information

Chemical Name:4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaMide
CAS No.:71005-94-2
Molecular Formula:C9H9ClN4O
Molecular Weight:224.64700
Hs Code.:
Mol file:71005-94-2.mol

Synonyms:4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide;4-Chloro-1ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxamide;4-Chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid amide;

Suppliers and Price of 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaMide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaMide

Chemical Property:

Melting Point:192 - 193 °C
Boiling Point:402.5±45.0 °C(Predicted)
PKA:14.46±0.30(Predicted)
PSA：73.80000
Density:1.56±0.1 g/cm3(Predicted)
LogP:1.90380

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaMide

There total 5 articles about 4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxaMide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52833-03-1
4-chloro-1-ethyl-1H-pyrazolo<3,4-b>pyridine-5-carbonyl chloride

: 71005-94-2
4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid amide

Guidance literature:: 4-chloro-1-ethyl-1H-pyrazolo<3,4-b>pyridine-5-carbonyl chloride; With ammonia; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; 1,4-dioxane; for 18h;

With ammonia; In tetrahydrofuran; 1,4-dioxane; for 72h;

Reference yield:

: 71005-93-1
4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonitrile

: 71005-94-2
4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid amide

Guidance literature:: With sulfuric acid; In ice-water;

Reference yield:

: 30720-04-8
1-ethyl-4-hydroxy-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid ethyl ester

: 71005-94-2
4-chloro-1-ethyl-1H-pyrazolo[3,4-b]pyridine-5-carboxylic acid amide

Guidance literature:: Multi-step reaction with 3 steps

1: ammonia / N-methyl-acetamide

2: thionyl chloride

3: sulfuric acid / ice-water

With thionyl chloride; sulfuric acid; ammonia; In N-methyl-acetamide; ice-water;