2-Propyn-1-ol, 3-(trimethylsilyl)-, 4-methylbenzenesulfonate

Base Information

Chemical Name:2-Propyn-1-ol, 3-(trimethylsilyl)-, 4-methylbenzenesulfonate
CAS No.:71321-16-9
Molecular Formula:C13H18O3SSi
Molecular Weight:282.436
Hs Code.:

Synonyms:2-Propyn-1-ol,3-(trimethylsilyl)-,4-methylbenzenesulfonate;3-(trimethylsilyl)prop-2-ynyl tosylate;

Suppliers and Price of 2-Propyn-1-ol, 3-(trimethylsilyl)-, 4-methylbenzenesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(Trimethylsilyl)-1-propyn-3-ylTosylate
5g
$ 1260.00

Total 0 raw suppliers

Chemical Property of 2-Propyn-1-ol, 3-(trimethylsilyl)-, 4-methylbenzenesulfonate

Chemical Property:

PSA：82.98000
LogP:3.18200

Purity/Quality:: 1-(Trimethylsilyl)-1-propyn-3-ylTosylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1-(Trimethylsilyl)-1-propyn-3-yl tosylate is used as a reagent to synthesize substituted anthracenes (e.g. B415000). 1-(Trimethylsilyl)-1-propyn-3-yl tosylate is also used as a reagent to synthesize (+)-crocacin A, a potent antifungal and cytotoxic agent.

Technology Process of 2-Propyn-1-ol, 3-(trimethylsilyl)-, 4-methylbenzenesulfonate

There total 2 articles about 2-Propyn-1-ol, 3-(trimethylsilyl)-, 4-methylbenzenesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 5272-36-6
3-trimethylsilyl-2-propyn-1-ol

: 98-59-9
p-toluenesulfonyl chloride

: 71321-16-9
3-(trimethylsilyl)prop-2-yn-1-yl 4-methylbenzenesulfonate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 0 - 20 ℃; for 2h;
DOI:10.1016/S0040-4039(03)01171-7

Reference yield:

: 71321-16-9
3-(trimethylsilyl)prop-2-yn-1-yl 4-methylbenzenesulfonate

Guidance literature:: DOI:10.1055/s-1979-28697

Reference yield: 70.0%

: 71321-16-9
3-(trimethylsilyl)prop-2-yn-1-yl 4-methylbenzenesulfonate

: 4559-70-0
Diphenylphosphine oxide

: diphenyl(1-(trimethylsilyl)propa-1,2-dien-1-yl)phosphine oxide

Guidance literature:: With 2,6-dimethylpyridine; trifluoromethylsulfonic anhydride; In dichloromethane; at 20 ℃; for 2h; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.orglett.9b03645