2H-Pyran-3(6H)-one, 6-(phenylmethoxy)-

Base Information

• Chemical Name: 2H-Pyran-3(6H)-one, 6-(phenylmethoxy)-
• CAS No.: 71443-23-7
• Molecular Formula: C12H12O3
• Molecular Weight: 204.225
• DSSTox Substance ID: DTXSID40444005
• Nikkaji Number: J1.419.855E
• Mol file: 71443-23-7.mol

Synonyms:2H-Pyran-3(6H)-one, 6-(phenylmethoxy)-;71443-23-7;6-benzoxy-6H-pyran-3-one;DTXSID40444005;6-(benzyloxy)-2H-pyran-3(6H)-one;2-(Benzyloxy)-2H-pyran-5(6H)-one

Chemical Property of 2H-Pyran-3(6H)-one, 6-(phenylmethoxy)-

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 204.078644241
• Heavy Atom Count: 15
• Complexity: 241

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(=O)C=CC(O1)OCC2=CC=CC=C2

Technology Process of 2H-Pyran-3(6H)-one, 6-(phenylmethoxy)-

There total 10 articles about 2H-Pyran-3(6H)-one, 6-(phenylmethoxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-O-benzoyl-2,3-dideoxy-D,L-pent-2-enopyranos-4-ulose (71443-22-6,63096-93-5) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 2,3-dideoxy-α,β-DL-pent-2-enopyranosid-4-ulose (71443-23-7)

Guidance literature:

zinc chloride diethyl ether; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1016/S0040-4039(01)80725-5

Reference yield: 82.0%

6-acetoxy-2H-pyran-3(6H)-one (62644-49-9) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 2,3-dideoxy-α,β-DL-pent-2-enopyranosid-4-ulose (71443-23-7)

Guidance literature:

With tin(IV) chloride; In dichloromethane; 1,2-dichloro-ethane; at 20 ℃; for 5h;

DOI:10.1016/S0040-4020(00)00846-2

Reference yield: 51.0%

6-hydroxy-3,6-dihydro-2H-pyran-3-one (35436-57-8) + benzyl alcohol (100-51-6,185532-71-2) → benzyl 2,3-dideoxy-α,β-DL-pent-2-enopyranosid-4-ulose (71443-23-7)

Guidance literature:

With perchloric acid; In acetone; for 0.0833333h; Ambient temperature;

DOI:10.1016/0008-6215(91)89015-8

upstream raw materials:

6-hydroxy-3,6-dihydro-2H-pyran-3-one

benzyl chloride

1-O-benzoyl-2,3-dideoxy-D,L-pent-2-enopyranos-4-ulose

benzyl alcohol

Downstream raw materials:

trans-4-Benzyloxy-5-hydroxy-2-cyclopenten-1-one