6-hydroxy-2H-pyran-3(6H)-one

Base Information

• Chemical Name: 6-hydroxy-2H-pyran-3(6H)-one
• CAS No.: 35436-57-8
• Molecular Formula: C5H6O3
• Molecular Weight: 114.101
• Hs Code.: 2932999099
• European Community (EC) Number: 803-679-9
• DSSTox Substance ID: DTXSID70445909
• Nikkaji Number: J813.386G
• Mol file: 35436-57-8.mol

Synonyms:6-hydroxy-2H-pyran-3(6H)-one;35436-57-8;6-hydroxy-6H-pyran-3-one;2-hydroxy-2H-pyran-5-one;6-HYDROXY-2,3-DIHYDRO-6H-PYRANO-3-ONE;SCHEMBL3371955;DTXSID70445909;2-Hydroxy-2H-pyran-5(6H)-one;6-Hydroxy-2,6-dihydropyran-3-one;MFCD02181121;SC1227;STL434967;AKOS022183503;3,6-dihydro-6-hydroxy-2h-pyran-3-one;DS-16512;CS-0063151;A874611

Chemical Property of 6-hydroxy-2H-pyran-3(6H)-one

Chemical Property:

• PSA: 46.53000
• LogP: -0.53970
• Storage Temp.: 2-8°C
• XLogP3: -0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 114.031694049
• Heavy Atom Count: 8
• Complexity: 128

Purity/Quality:

97% ^*data from raw suppliers

6-Hydroxy-2H-pyran-3(6H)-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(=O)C=CC(O1)O

Technology Process of 6-hydroxy-2H-pyran-3(6H)-one

There total 14 articles about 6-hydroxy-2H-pyran-3(6H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(2-furyl)methyl alcohol (98-00-0,25212-86-6,93793-62-5) → 6-hydroxy-3,6-dihydro-2H-pyran-3-one (35436-57-8)

Guidance literature:

With oxygen; 5,15,10,20-tetraphenylporphyrin; triphenylphosphine; In dichloromethane; at -70 ℃; for 2h; Product distribution; Mechanism; Irradiation; other substituted 2-furylcarbinols;

DOI:10.3987/COM-90-5433

Reference yield: 95.0%

2,5-dimethoxy-2-hydroxymethyl-2,5-dihydrofuran (19969-71-2) → 6-hydroxy-3,6-dihydro-2H-pyran-3-one (35436-57-8)

Guidance literature:

With sulfuric acid; for 0.5h; Ambient temperature;

Reference yield: 90.0%

5,5-diethoxy-1,4-dihydroxypentan-2-one (1416054-94-8) → 6-hydroxy-3,6-dihydro-2H-pyran-3-one (35436-57-8)

Guidance literature:

With tetrafluoroboric acid; In acetonitrile; at 20 ℃; for 18h;

DOI:10.1002/hlca.201200423

upstream raw materials:

(2-furyl)methyl alcohol

2,5-dimethoxy-2-hydroxymethyl-2,5-dihydrofuran

furfural

4,4,5,5-tetraethoxypent-2-yn-1-ol

Downstream raw materials:

benzyl 4-O-(2,3-dideoxy-α-L-pent-2-enopyranosyl-4-ulose)-2,3-O-isopropylidene-α-L-rhamnopyranoside

benzyl 4-O-(2,3-dideoxy-α-D-pent-2-enopyranosyl-4-ulose)-2,3-O-isopropylidene-α-L-rhamnopyranoside

6-<(S)-2-(Benzyloxycarbonylamino)-3-phenylpropoxy>-2H-pyran-3(6H)-one

(R)-6-[(2R,3R,6S)-3-(4-Bromo-phenoxy)-6-ethoxy-3,6-dihydro-2H-pyran-2-ylmethoxy]-6H-pyran-3-one