Technology Process of Ortetamine
There total 6 articles about Ortetamine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
10-phenyl-9-(2,4,6-trimethylphenyl)acridinium tetrafluoroborate; ammonium carbonate; 2-amino-benzenethiol;
In
dichloromethane; chlorobenzene;
at 20 ℃;
for 12h;
Schlenk technique;
Inert atmosphere;
Sealed tube;
Irradiation;
DOI:10.1002/anie.202016679
- Guidance literature:
-
With
hydrogenchloride; sodium cyanoborohydride;
In
methanol;
at 20 ℃;
for 24h;
DOI:10.1002/adsc.202100351
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dichloro bis(acetonitrile) palladium(II); 9-(2-mesityl)-10-methylacridinium perchlorate / acetonitrile / 16 h / 20 °C
2: sodium cyanoborohydride; hydrogenchloride / methanol / 24 h / 20 °C
With
hydrogenchloride; dichloro bis(acetonitrile) palladium(II); sodium cyanoborohydride; 9-(2-mesityl)-10-methylacridinium perchlorate;
In
methanol; acetonitrile;
1: |Wacker-Tsuji Olefin Oxidation;
DOI:10.1002/adsc.202100351
