2-Oxabicyclo[2.2.1]heptan-3-one, 1,7,7-trimethyl-

Base Information

• Chemical Name: 2-Oxabicyclo[2.2.1]heptan-3-one, 1,7,7-trimethyl-
• CAS No.: 19893-77-7
• Molecular Formula: C9H14 O2
• Molecular Weight: 154.209
• Hs Code.: 2932209090
• Mol file: 19893-77-7.mol

Synonyms:Campholytolactone;Camphorlactone; a-Campholytolactone

Chemical Property of 2-Oxabicyclo[2.2.1]heptan-3-one, 1,7,7-trimethyl-

Chemical Property:

• Melting Point: 156-157 °C
• Boiling Point: 226.5±8.0 °C(Predicted)
• PSA: 26.30000
• Density: 1.056±0.06 g/cm3(Predicted)
• LogP: 1.73810

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Oxabicyclo[2.2.1]heptan-3-one, 1,7,7-trimethyl-

There total 7 articles about 2-Oxabicyclo[2.2.1]heptan-3-one, 1,7,7-trimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one (736109-58-3,787517-91-3,68546-28-1) → Camphorquinone (2767-84-2,10334-26-6,10373-78-1,71074-96-9,105309-30-6,465-29-2) + 1,7,7-trimethyl-2-oxa-bicyclo[2.2.1]heptan-3-one (19893-77-7)

Guidance literature:

With Calcium tetrakis(pentafluorophenyl)borate; dihydrogen peroxide; oxalic acid; In water; 1,2-dichloro-ethane; at 50 ℃; for 18h; Reagent/catalyst;

Reference yield:

→ 1,7,7-trimethyl-2-oxa-bicyclo[2.2.1]heptan-3-one (19893-77-7)

Guidance literature:

With acetic anhydride; lactone of/the/ dextrorotatory trans-oxydihydro-α-campholytic acid;

Reference yield:

camphoric acid (306279-95-8) → 4,7,7-trimethyl-2-oxa-bicyclo[2.2.1]heptan-3-one (54812-08-7) + 1,7,7-trimethyl-2-oxa-bicyclo[2.2.1]heptan-3-one (19893-77-7)

Guidance literature:

With pyridine; lead(IV) acetate; In benzene; for 6h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; Heating;

upstream raw materials:

camphoric acid

methyl magnesium iodide

1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one

Refernces

• 1、 McCoy,Zagalo. "-". . p. 824,825. Retrieved 1960.
• 2、 Shitole, H.R.,Deshpande, R.P.,Nayak, U.R.. "Lead Tetraacetate Reaction on Dicarboxylic Acids: Synthesis of Some Novel Longifolene-derived Oxygen Heterocycloes". . p. 418 - 423. Retrieved 2007/10/02.