Cyclohexanecarboxylic acid, 1-(2-propynyl)-

Base Information

Chemical Name:Cyclohexanecarboxylic acid, 1-(2-propynyl)-
CAS No.:72335-52-5
Molecular Formula:C10H14O2
Molecular Weight:166.21700
Hs Code.:

Synonyms:Cyclohexanecarboxylic acid,1-(2-propynyl);1-propargyl-1-cyclohexyl-carboxylic acid;1-(prop-2-ynyl)cyclohexanecarboxylic acid;

Suppliers and Price of Cyclohexanecarboxylic acid, 1-(2-propynyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(prop-2-yn-1-yl)cyclohexane-1-carboxylicacid
50mg
$ 220.00

TRC
1-(prop-2-yn-1-yl)cyclohexane-1-carboxylicacid
10mg
$ 65.00

AK Scientific
1-(Prop-2-yn-1-yl)cyclohexane-1-carboxylicacid
100mg
$ 407.00

Total 3 raw suppliers

Chemical Property of Cyclohexanecarboxylic acid, 1-(2-propynyl)-

Chemical Property:

PSA：37.30000
LogP:2.04480

Purity/Quality:

99% ^*data from raw suppliers

1-(prop-2-yn-1-yl)cyclohexane-1-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Cyclohexanecarboxylic acid, 1-(2-propynyl)-

There total 3 articles about Cyclohexanecarboxylic acid, 1-(2-propynyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 678988-77-7
methyl 1-(prop-2-yn-1-yl)cyclohexane-1-carboxylate

: 72335-52-5
1-(prop-2-yn-1-yl)cyclohexane-1-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; for 24h; Inert atmosphere; Reflux;
DOI:10.1021/ja906744r

Reference yield:

: 106-96-7
propargyl bromide

: 98-89-5
Cyclohexanecarboxylic acid

: 72335-52-5
1-(prop-2-yn-1-yl)cyclohexane-1-carboxylic acid

Guidance literature:: With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane;

Reference yield:

: 4630-82-4
methyl cyclohexylcarboxylate

: 72335-52-5
1-(prop-2-yn-1-yl)cyclohexane-1-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 1.17 h / -78 °C / Inert atmosphere

1.2: 2 h / -78 - 25 °C / Inert atmosphere

2.1: potassium hydroxide / water; methanol / 4 h / 0 - 20 °C

With potassium hydroxide; lithium diisopropyl amide; In tetrahydrofuran; methanol; n-heptane; ethylbenzene; water;
DOI:10.1002/adsc.201600492