4-[(Z)-2-Hydroxyethylidene]-6,6-dimethyl-2-cyclohexen-1-ol

Base Information

• Chemical Name: 4-[(Z)-2-Hydroxyethylidene]-6,6-dimethyl-2-cyclohexen-1-ol
• CAS No.: 73872-82-9
• Molecular Formula: C10H16O2
• Molecular Weight: 168.23300
• Mol file: 73872-82-9.mol

Synonyms:(R)-4-[2-Hydroxy-eth-(Z)-ylidene]-6,6-dimethyl-cyclohex-2-enol;

Chemical Property of 4-[(Z)-2-Hydroxyethylidene]-6,6-dimethyl-2-cyclohexen-1-ol

Chemical Property:

• Boiling Point: 291.6±28.0 °C(Predicted)
• PKA: 14.20±0.40(Predicted)
• PSA: 40.46000
• Density: 1.122±0.06 g/cm3(Predicted)
• LogP: 1.25210

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-[(Z)-2-Hydroxyethylidene]-6,6-dimethyl-2-cyclohexen-1-ol

There total 18 articles about 4-[(Z)-2-Hydroxyethylidene]-6,6-dimethyl-2-cyclohexen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

5,6-epoxy-2-ochtoden-1-ol (82528-45-8,82528-51-6,95495-66-2,95495-75-3) → (+/-)-(2Z)-2,4-ochtodadiene-1,6-diol (73872-82-9)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 - -20 ℃; for 2h;

DOI:10.1016/S0040-4039(00)87138-5

Reference yield: 61.0%

5-phenylseleno-2-ochtodene-1,6-diol (82528-47-0) → (+/-)-(2Z)-2,4-ochtodadiene-1,6-diol (73872-82-9)

Guidance literature:

With sodium periodate; In methanol; water; 0 deg C, 15 min, room temperature, 7 h;

DOI:10.1246/bcsj.57.3466

Reference yield: 55.0%

5-phenylseleno-2-ochtodene-1,6-diol (82528-47-0) → 2,4-ochtodien-1,6-diol (73872-82-9,73891-29-9,89197-95-5,95495-67-3,97885-79-5)

Guidance literature:

With sodium periodate; In methanol; water; at 15 ℃; for 7h;

DOI:10.1016/S0040-4039(00)87138-5

upstream raw materials:

vinyl magnesium bromide

4-bromo-5,5-dimethyl-2-cyclohexen-1-one

5-phenylseleno-2-ochtodene-1,6-diol

5,5-dimethlycyclohex-2-en-1-one

Downstream raw materials:

[5,5-Dimethyl-4-oxo-cyclohex-2-en-(Z)-ylidene]-acetaldehyde

Acetic acid (R)-4-[2-acetoxy-eth-(Z)-ylidene]-6,6-dimethyl-cyclohex-2-enyl ester