1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl-

Base Information

Chemical Name:1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl-
CAS No.:74074-84-3
Molecular Formula:C17H18O3S
Molecular Weight:302.394
Hs Code.:
DSSTox Substance ID:DTXSID70541051
Nikkaji Number:J469.825H
Wikidata:Q82417262

Synonyms:74074-84-3;1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl-;2-Methyl-2-(4-methylbenzene-1-sulfonyl)-1-phenylpropan-1-one;2-methyl-1-phenyl-2-tosylpropan-1-one;SCHEMBL209160;2-methyl-2-(4-methylphenyl)sulfonyl-1-phenylpropan-1-one;DTXSID70541051;WBXCFSRAWFNBHW-UHFFFAOYSA-N;2-methyl-2-(p-toluenesulfonyl)propiophenone

Suppliers and Price of 1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl-

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:302.09766561
Heavy Atom Count:21
Complexity:459

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)C(C)(C)C(=O)C2=CC=CC=C2

Technology Process of 1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl-

There total 4 articles about 1-Propanone, 2-methyl-2-[(4-methylphenyl)sulfonyl]-1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 7473-99-6
α-chloroisobutyrophenone

: 824-79-3
sodium 4-methylbenzenesulfinate

: 74074-84-3
α-(p-methylbenzenesulfonyl)isobutyrophenone

Guidance literature:: With potassium tert-butylate; In dimethyl sulfoxide; at 60 ℃; for 16h; Irradiation;
DOI:10.1021/ja00294a050

Reference yield: 80.0%

: 10409-54-8
2-bromo-2-methyl-1-phenyl-propan-1-one

: tetrabutylammonium 4-methylbenzenesulfinate

: 74074-84-3
α-(p-methylbenzenesulfonyl)isobutyrophenone

Guidance literature:: In tetrahydrofuran; 1.) 6h, 50 deg C, 2.) 16h, 20 deg C;

Reference yield:

: 611-70-1
phenyl isopropyl ketone

: 74074-84-3
α-(p-methylbenzenesulfonyl)isobutyrophenone

Guidance literature:: Multi-step reaction with 2 steps

1: bromine / dichloromethane / 20 °C / Inert atmosphere

2: copper(II) bis(trifluoromethanesulfonate); caesium carbonate; water / toluene / 20 h / 70 °C / Schlenk technique; Inert atmosphere

With water; bromine; copper(II) bis(trifluoromethanesulfonate); caesium carbonate; In dichloromethane; toluene;
DOI:10.1021/acs.joc.6b00844