Benzeneethanimidoyl chloride, N-(1-methylethyl)-

Base Information

• Chemical Name: Benzeneethanimidoyl chloride, N-(1-methylethyl)-
• CAS No.: 74157-83-8
• Molecular Formula: C₁₁H₁₄ClN
• Molecular Weight: 195.692
• Mol file: 74157-83-8.mol

Synonyms:

Chemical Property of Benzeneethanimidoyl chloride, N-(1-methylethyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzeneethanimidoyl chloride, N-(1-methylethyl)-

There total 3 articles about Benzeneethanimidoyl chloride, N-(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.7%

N-isopropyl-2-phenylacetamide (5215-54-3) → N-isopropylphenylacetimidoyl chloride (74157-83-8)

Guidance literature:

With phosphorus pentachloride; In benzene; for 1h; Heating;

Reference yield:

phenylacetic acid (103-82-2) → N-isopropylphenylacetimidoyl chloride (74157-83-8)

Guidance literature:

Multi-step reaction with 3 steps

1: thionyl chloride / benzene

2: triethylamine / diethyl ether / 5 h / Ambient temperature

3: PCl₅ / benzene / 1 h / Heating

With thionyl chloride; phosphorus pentachloride; triethylamine; In diethyl ether; benzene;

DOI:10.1039/P29800000579

Reference yield:

phenylacetyl chloride (103-80-0) → N-isopropylphenylacetimidoyl chloride (74157-83-8)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / diethyl ether / 5 h / Ambient temperature

2: PCl₅ / benzene / 1 h / Heating

With phosphorus pentachloride; triethylamine; In diethyl ether; benzene;

DOI:10.1039/P29800000579

upstream raw materials:

N-isopropyl-2-phenylacetamide

phenylacetic acid

phenylacetyl chloride

Downstream raw materials:

N-isopropylphenylketenimine

N-Isopropyl-N-phenylacetyl-acetamide

Refernces

• 1、 McCarthy, Daniel G.,Hegarty, Anthony F.. "Rapid Acid-catalysed and Uncatalysed Hydration of Ketenimines". . p. 579 - 591. Retrieved 2007/10/02.