FENOPROFEN CALCIUM

Base Information

• Chemical Name: FENOPROFEN CALCIUM
• CAS No.: 34597-40-5
• Molecular Formula: 2C₁₅H₁₃O₃*Ca
• Molecular Weight: 522.611
• Mol file: 34597-40-5.mol

Synonyms:Benzeneaceticacid, a-methyl-3-phenoxy-, calcium salt(9CI); Benzeneacetic acid, a-methyl-3-phenoxy-, calcium salt, (?à)-; 2-(3-Phenoxyphenyl)propionic acid calcium salt;Calcium fenoprofen; Fenoprofen calcium; Nalfon; Trandor

Chemical Property of FENOPROFEN CALCIUM

Chemical Property:

• Vapor Pressure: 1.71E-06mmHg at 25°C
• Boiling Point: 381.3°Cat760mmHg
• Flash Point: 141.7°C
• PSA: 71.06000
• Density: 1.183g/cm³
• LogP: 7.17980
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

98%Min ^*data from raw suppliers

Fenoprofen calcium >99% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Anti-inflammatory; analgesic.

Technology Process of FENOPROFEN CALCIUM

There total 2 articles about FENOPROFEN CALCIUM which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

NH2 + aqueous alcohol + aqueous calcium chloride + Fenoprofen (29679-58-1,31879-05-7,32953-79-0) + pyrographite (7440-44-0) → fenoprofen calcium (34597-40-5,56367-29-4)

Guidance literature:

In (2S)-N-methyl-1-phenylpropan-2-amine hydrate;

Reference yield:

calcium 2-(3-phenoxyphenyl) propanoate dihydrate → fenoprofen calcium (34597-40-5,56367-29-4)

Guidance literature:

In water; at 50 ℃; Further Variations:; Temperatures; Kinetics;

DOI:10.1002/jps.1038

Reference yield:

fenoprofen calcium (34597-40-5,56367-29-4) + β‐cyclodextrin (7585-39-9) → C42H70O35*C15H14O3 (115245-44-8)

Guidance literature:

In water; ethyl acetate; at 50 ℃; for 2h;

DOI:10.1021/ja00225a039

upstream raw materials:

Fenoprofen

pyrographite

Downstream raw materials:

methyl 2-(3-phenoxybenzene)propionate

C₄₂H₇₀O₃₅*C₁₅H₁₄O₃

4,5α-epoxy-3-methoxy-17-methyl-morphin-7-en-6α-ol; 2-(3-phenoxy-phenyl)-propionate (fenoprofenate)

Refernces

• 1、 -. "Process for the preparation of 2-(3-phenoxy-phenyl)-propionic acid". . . Retrieved 2008/06/13.