Carbamic acid, [1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[ (1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl ]amino]-3-oxopropyl]-4-piperidinyl ester

Base Information

Chemical Name:Carbamic acid, [1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[ (1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl ]amino]-3-oxopropyl]-4-piperidinyl ester
CAS No.:743461-64-5
Molecular Formula:C46H56ClN5O7Si
Molecular Weight:854.518
Hs Code.:

Carbamic acid, [1,1'-biphenyl]-2-yl-,
1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[
(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl
]amino]-3-oxopropyl]-4-piperidinyl ester

Synonyms:

Suppliers and Price of Carbamic acid, [1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[ (1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl ]amino]-3-oxopropyl]-4-piperidinyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Carbamic acid, [1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[ (1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl ]amino]-3-oxopropyl]-4-piperidinyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Carbamic acid, [1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[ (1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl ]amino]-3-oxopropyl]-4-piperidinyl ester

There total 14 articles about Carbamic acid, [1,1'-biphenyl]-2-yl-, 1-[3-[[2-chloro-4-[[[(2R)-2-(1,2-dihydro-8-hydroxy-2-oxo-5-quinolinyl)-2-[[ (1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]amino]methyl]-5-methoxyphenyl ]amino]-3-oxopropyl]-4-piperidinyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 100331-89-3
8-benzyloxy-5-(2-bromoacetyl)-1H-quinolin-2-one

: 743461-63-4
biphenyl-2-ylcarbamic Acid 1-[2-(2-Chloro-4-formyl-5-methoxyphenylcarbamoyl)-ethyl]piperidin-4-yl Ester

: 743461-64-5
biphenyl-2-ylcarbamic Acid 1-[2-(4-{[(R)-2-(tert-Butyldimethylsilanyloxy)-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-2-chloro-5-methoxy-phenylcarbamoyl)ethyl]piperidin-4-yl Ester

Guidance literature:: 8-benzyloxy-5-(2-bromoacetyl)-1H-quinolin-2-one; biphenyl-2-ylcarbamic Acid 1-[2-(2-Chloro-4-formyl-5-methoxyphenylcarbamoyl)-ethyl]piperidin-4-yl Ester; In methanol; dichloromethane; at 0 - 20 ℃; for 2h;

With sodium tris(acetoxy)borohydride; In methanol; dichloromethane; at 0 - 20 ℃; for 2.16667h; Product distribution / selectivity;

Reference yield: 85.0%

: 743461-21-4
5-((1R)-2-amino-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl)-8-hydroxyquinolin-2(1H)-one

: 743461-63-4
biphenyl-2-ylcarbamic Acid 1-[2-(2-Chloro-4-formyl-5-methoxyphenylcarbamoyl)-ethyl]piperidin-4-yl Ester

: 743461-64-5
biphenyl-2-ylcarbamic Acid 1-[2-(4-{[(R)-2-(tert-Butyldimethylsilanyloxy)-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-2-chloro-5-methoxy-phenylcarbamoyl)ethyl]piperidin-4-yl Ester

Guidance literature:: 5-((1R)-2-amino-1-{[tert-butyl(dimethyl)silyl]oxy}ethyl)-8-hydroxyquinolin-2(1H)-one; biphenyl-2-ylcarbamic Acid 1-[2-(2-Chloro-4-formyl-5-methoxyphenylcarbamoyl)-ethyl]piperidin-4-yl Ester; In methanol; dichloromethane; at 25 ℃; for 2h;

With sodium tris(acetoxy)borohydride; In methanol; dichloromethane; at 25 ℃; for 24h;