6-Azabicyclo[3.2.1]octane-6-carboxylic acid, 7-oxo-2-[(3S)-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]-1-pyrrolidinyl]-, 1,1-dimethylethyl ester, (1R,2S,5R)-

Base Information

Chemical Name:6-Azabicyclo[3.2.1]octane-6-carboxylic acid, 7-oxo-2-[(3S)-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]-1-pyrrolidinyl]-, 1,1-dimethylethyl ester, (1R,2S,5R)-
CAS No.:746671-17-0
Molecular Formula:C24H31N3O6
Molecular Weight:457.527
Hs Code.:

6-Azabicyclo[3.2.1]octane-6-carboxylic acid,
7-oxo-2-[(3S)-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]-1-pyrrolidinyl]-,
1,1-dimethylethyl ester, (1R,2S,5R)-

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Chemical Property of 6-Azabicyclo[3.2.1]octane-6-carboxylic acid, 7-oxo-2-[(3S)-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]-1-pyrrolidinyl]-, 1,1-dimethylethyl ester, (1R,2S,5R)-

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Technology Process of 6-Azabicyclo[3.2.1]octane-6-carboxylic acid, 7-oxo-2-[(3S)-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]-1-pyrrolidinyl]-, 1,1-dimethylethyl ester, (1R,2S,5R)-

There total 5 articles about 6-Azabicyclo[3.2.1]octane-6-carboxylic acid, 7-oxo-2-[(3S)-2-oxo-3-[[(phenylmethoxy)carbonyl]amino]-1-pyrrolidinyl]-, 1,1-dimethylethyl ester, (1R,2S,5R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 1004536-58-6
C₂₆H₃₈N₃O₆S⁽¹⁺⁾*I^(1-)

: 746671-17-0
tert-butyl (1R,2S,5R)-2-((S)-3-(((benzyloxy)carbonyl)amino)-2-oxopyrrolidin-1-yl)-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate

Guidance literature:: With caesium carbonate; In dimethyl sulfoxide; at 20 ℃; for 3h;

Reference yield:

: 847955-65-1
tert-butyl (1R,2S,5R)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-(methylthio)butanamido)-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate

: 746671-17-0
tert-butyl (1R,2S,5R)-2-((S)-3-(((benzyloxy)carbonyl)amino)-2-oxopyrrolidin-1-yl)-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate

Guidance literature:: tert-butyl (1R,2S,5R)-2-((S)-2-(((benzyloxy)carbonyl)amino)-4-(methylthio)butanamido)-7-oxo-6-azabicyclo[3.2.1]octane-6-carboxylate; With methyl iodide; at 20 ℃; for 12h;

With caesium carbonate; In DMF (N,N-dimethyl-formamide); for 12h;